The Administrative Core provides leadership and support to promote the highest quality research in the DEARC and its impact. The goals of the Administrative Core are to facilitate interactions among projects and attain research excellence throughout the DEARC by providing clear leadership, efficient management, effective committee structure, strong administrative, fiscal and research infrastructure, and the promotion of integration and synergism. These goals are supported through 5 aims.
Aim 1 provides an organizational infrastructure to facilitate attainment of Center goals and objectives through a strong Executive Committee (EC) consisting of the PI (L. Spear) and the two co-l's (T. Deak &S. Youngentob) of the Administrative Core, aided by an efficient DEARC office and administrator, capable fiscal support through the State University of New York Research Foundation (with offices at both Binghamton University [BU] and Upstate Medical University [UMU]), as well as strong institutional support and an impressive research infrastructure that includes new animal buildings on both DEARC campuses. Building on the culture of collaboration within the DEARC, Aim 2 promotes communication, facilitates interactions and encourages integration and synergisms across the DEARC through such activities as monthly meetings, mini-retreats, DEARC-sponsored colloquia, and a yearly retreat.
Aims 3 and 4 are to ensure oversight, coordinate interactions among research projects and cores, promote research-supportive allocation of resources, and utilize internal and external guidance committees to ensure quality and progress of research components and cores. Day-to-day decisions will be made by the EC with frequent consultation of a Steering Committee (composed of PIs of cores and main projects) and oversight by two critical guidance committees: an Internal Advisory Board (lAB) comprised of administrators at BU and UMU, and an External Advisory Board (EAB) comprised of nationally prominent senior alcohol researchers who serve as a program advisory committee to evaluate and advise the DEARC regarding all aspects of Center functioning.
Aim 5 is to encourage enrichment at all career levels, promote the recruitment of new researchers in the field of alcohol and development, and enhance outreach efforts.

Public Health Relevance

The success of the Developmental Exposure Alcohol Research Center (DEARC) relies on an effective Administrative Core to facilitate interactions across the DEARC and promote the highest quality research in the area of alcohol and development. These goals will be accomplished through a strong Executive Committee, assisted by other internal and external committees, strong infrastructure and institutional support, as well as the already established culture of collaboration within the DEARC.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Specialized Center (P50)
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Study Section
Special Emphasis Panel (ZAA1)
Program Officer
Witt, Ellen
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State University of NY, Binghamton
United States
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Gano, Anny; Doremus-Fitzwater, Tamara L; Deak, Terrence (2016) Sustained alterations in neuroimmune gene expression after daily, but not intermittent, alcohol exposure. Brain Res 1646:62-72
Doremus-Fitzwater, Tamara L; Spear, Linda P (2016) Reward-centricity and attenuated aversions: An adolescent phenotype emerging from studies in laboratory animals. Neurosci Biobehav Rev 70:121-134
Diaz, Marvin R; Mooney, Sandra M; Varlinskaya, Elena I (2016) Acute prenatal exposure to ethanol on gestational day 12 elicits opposing deficits in social behaviors and anxiety-like behaviors in Sprague Dawley rats. Behav Brain Res 310:11-9
Eade, Amber M; Youngentob, Lisa M; Youngentob, Steven L (2016) The Interaction of Ethanol Ingestion and Social Interaction with an Intoxicated Peer on the Odor-Mediated Response to the Drug in Adolescent Rats. Alcohol Clin Exp Res 40:734-42
Fernández, Macarena Soledad; Fabio, María Carolina; Miranda-Morales, Roberto Sebastián et al. (2016) Age-related effects of chronic restraint stress on ethanol drinking, ethanol-induced sedation, and on basal and stress-induced anxiety response. Alcohol 51:89-100
Spear, Linda Patia (2016) Consequences of adolescent use of alcohol and other drugs: Studies using rodent models. Neurosci Biobehav Rev 70:228-243
Saalfield, Jessica; Spear, Linda (2016) The ontogeny of ethanol aversion. Physiol Behav 156:164-70
Santerre, J L; Kolitz, E B; Pal, R et al. (2015) Cytoplasmic phospholipase Aâ‚‚ modulation of adolescent rat ethanol-induced protein kinase C translocation and behavior. Neurochem Res 40:1023-31
Deak, Terrence; Hunt, Pamela S (2015) Early ontogeny as a unique developmental epoch for learning, memory and consequences of alcohol exposure: A Festschrift to honor the work of Dr. Norman E. Spear. Physiol Behav 148:1-5
Doremus-Fitzwater, Tamara L; Gano, Anny; Paniccia, Jacqueline E et al. (2015) Male adolescent rats display blunted cytokine responses in the CNS after acute ethanol or lipopolysaccharide exposure. Physiol Behav 148:131-44

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