The Education Core (Core E) of the Johns Hopkins Alzheimer's Disease Research Center (ADRC) has several overarching goals: (1) To augment mechanisms for recruiting and retaining subjects into the clinical research activities of the ADRC, and to assure that this subject population reflects the ethnic and racial diversity of the Greater Balfimore area. (2) To increase the knowledge about AD and related disorders among patients, caregivers and other community members concerning: (a) diagnosis and management of AD and related disorders, (b) age-related changes of cognition and risk factors for cognifive decline, and (c) signs and symptoms of mild cognifive impairment, and the transition to dementia. (3) To expand educafional opportunifies for professionals at all stages of development, including: medical students, residents, post-doctoral fellows, junior faculty and established clinicians, as well as those in allied professions, such as nursing and social work. In this context, it is especially important to develop educafional opportunifies for clinicians that provide care to underserved segments ofthe community. In the current funding cycle, we have ufilized a set of educafional principals in order to help us establish priorities, and to plan and evaluate our programs. Through the efforts of the Education Core, working with the Clinical Core, we have been able to increase minority enrollment in the Clinic Cohort from 16% to 26%. In the next funding cycle, we will aim to maintain this diverse group of subjects and to encourage their participation in projects associated with the ADRC and participate in ante-mortem autopsy approval. During the current funding cycle, the Education Core has also provided a wide variety of educational programs for the lay public and for professionals. We will continue to evaluate these programs to assure they are meeting their programmatic aims and will initiate new programs that address the mission of the ADRC and educational efforts related to AD and related disorders throughout the U.S. more broadly.

Public Health Relevance

The Johns Hopkins Alzheimer's Disease Research Center (ADRC) will address many of the topics important to dementia research, with a particular focus on the understanding the eariiest phases of Alzheimer's disease (AD). This approach is important if we are ultimately going to be able to diagnose and treat AD as eariy as possible. The ADRC fosters interactions among scientists who are pursuing this overarching theme.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005146-28
Application #
8440983
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4)
Project Start
1997-07-15
Project End
2015-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
28
Fiscal Year
2011
Total Cost
$84,428
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Hibar, Derrek P (see original citation for additional authors) (2017) Novel genetic loci associated with hippocampal volume. Nat Commun 8:13624
Haberman, Rebecca P; Koh, Ming Teng; Gallagher, Michela (2017) Heightened cortical excitability in aged rodents with memory impairment. Neurobiol Aging 54:144-151
Jeong, Yun Ha; Ling, Jonathan P; Lin, Sophie Z et al. (2017) Tdp-43 cryptic exons are highly variable between cell types. Mol Neurodegener 12:13
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2017) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord :
Rawlings, Andreea M; Sharrett, A Richey; Mosley, Thomas H et al. (2017) Glucose Peaks and the Risk of Dementia and 20-Year Cognitive Decline. Diabetes Care 40:879-886
Mori, Susumu; Kageyama, Yusuke; Hou, Zhipeng et al. (2017) Elucidation of White Matter Tracts of the Human Amygdala by Detailed Comparison between High-Resolution Postmortem Magnetic Resonance Imaging and Histology. Front Neuroanat 11:16
Valera, Elvira; Spencer, Brian; Mott, Jennifer et al. (2017) MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy. Front Mol Neurosci 10:329
Brenowitz, Willa D; Keene, C Dirk; Hawes, Stephen E et al. (2017) Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples. Neurobiol Aging 53:83-92
Gross, Alden L; Hassenstab, Jason J; Johnson, Sterling C et al. (2017) A classification algorithm for predicting progression from normal cognition to mild cognitive impairment across five cohorts: The preclinical AD consortium. Alzheimers Dement (Amst) 8:147-155
Liu, Peiying; Li, Yang; Pinho, Marco et al. (2017) Cerebrovascular reactivity mapping without gas challenges. Neuroimage 146:320-326

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