OUTREACH, RECRUITMENT, AND EDUCATION CORE (CORE E) - PROJECT SUMMARY The overall goal of the Outreach, Recruitment and Education (ORE) Core is to improve the care provided to persons and families affected by Alzheimer's disease (AD) and related dementias by disseminating information and translating new knowledge into practice for researchers, health care professionals, trainees and the general public. The activities of the ORE Core represent a collaborative initiative involving the Section of Geriatrics and Gerontology, the Wisconsin Alzheimer's Association Chapter Network (WAACN), Office of Continuing Professional Development in Medicine and Public Health (OCPD), Medical College of Wisconsin (MCW), State of Wisconsin Department of Health Services (DHS), Wisconsin Geriatric Education Center (WGEC), communities throughout Wisconsin and the extensive outreach, community education and dementia diagnostic clinic programs of the Wisconsin Alzheimer's Institute (WAI). These collaborations represent a unique leveraging of resources to expand the influence of the ORE Core beyond the walls of the University of Wisconsin School of Medicine and Public Health (UW SMPH). The ORE Core is fully integrated into the Clinical, Neuropathology, and Data Management and Statistical Cores as well as the Minority Recruitment Satellite Program (MRSP). Working together, the Core has been able to identify and resolve the barriers to research participation by a diverse study population. Our successful recruitment efforts are matched by our clinical and research education and training programs and the statewide outreach and professional education programs of the WAI. Over the past 4 years, the Core's outreach, recruitment and education programs have worked to achieve the stated goals of the National Alzheimer's Project Act (NAPA) by enhancing public awareness and engagement, optimizing care quality and efficiency and working with health providers and state government to expand supports for persons with AD and their families. The Core has made major contributions to NAPA's primary goal to prevent and effectively treat AD by 2025 by supporting clinical trials and the study of preclinical AD, mild cognitive impairment (MCI) and AD at the Wisconsin Alzheimer's Disease Research Center (ADRC) and the WAI (Wisconsin Registry of Alzheimer's Prevention: Biomarkers of Preclinical AD, RO1AG27161-5) [2-4]. These efforst and collaborations will be expanded during this renewal and new programs will be added to ensure ongoing success of the ORE Core.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZAG1-ZIJ-4 (J1))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Wisconsin Madison
United States
Zip Code
Willette, Auriel A; Johnson, Sterling C; Birdsill, Alex C et al. (2015) Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Alzheimers Dement 11:504-510.e1
Joshi, Gururaj; Gan, Kok Ann; Johnson, Delinda A et al. (2015) Increased Alzheimer's disease-like pathology in the APP/ PS1?E9 mouse model lacking Nrf2 through modulation of autophagy. Neurobiol Aging 36:664-79
Engelman, Corinne D; Koscik, Rebecca L; Jonaitis, Erin M et al. (2014) Investigation of triggering receptor expressed on myeloid cells 2 variant in the Wisconsin Registry for Alzheimer's Prevention. Neurobiol Aging 35:1252-4
Kim, Hyunwoo J; Adluru, Nagesh; Bendlin, Barbara B et al. (2014) Canonical Correlation Analysis on Riemannian Manifolds and Its Applications. Comput Vis ECCV 8690:251-267
Hoy, Andrew R; Koay, Cheng Guan; Kecskemeti, Steven R et al. (2014) Optimization of a free water elimination two-compartment model for diffusion tensor imaging. Neuroimage 103:323-33
Okonkwo, Ozioma C; Oh, Jennifer M; Koscik, Rebecca et al. (2014) Amyloid burden, neuronal function, and cognitive decline in middle-aged adults at risk for Alzheimer's disease. J Int Neuropsychol Soc 20:422-33
Mielke, Michelle M; Haughey, Norman J; Bandaru, Veera V R et al. (2014) Cerebrospinal fluid sphingolipids, ?-amyloid, and tau in adults at risk for Alzheimer's disease. Neurobiol Aging 35:2486-94
Fischer, Barbara L; Gleason, Carey E; Gangnon, Ronald E et al. (2014) Declining cognition and falls: role of risky performance of everyday mobility activities. Phys Ther 94:355-62
Johnson, Sterling C; Christian, Bradley T; Okonkwo, Ozioma C et al. (2014) Amyloid burden and neural function in people at risk for Alzheimer's Disease. Neurobiol Aging 35:576-84
Okonkwo, Ozioma C; Schultz, Stephanie A; Oh, Jennifer M et al. (2014) Physical activity attenuates age-related biomarker alterations in preclinical AD. Neurology 83:1753-60

Showing the most recent 10 out of 46 publications