The purpose of the administrative core of this Tropical Medicine Research Center is to coordinate all administrative, scientific, travel-related, and meeting activities of the program. Our Research Administrator, Elbe Silva, has coordinated activities of the Immunology group at UFBA for many years, and is very familiar with all activities described in this core. Ms. Silva will provide direct assistance to the Core Director, Dr. Carvalho. The core co-Directors, Drs. Johnson and Wilson, have been involved in the Bahia research program since 1969 and 1998, respectively. The specific functions of the Administrative core are: 1. To provide administrative coordination for the three projects and for the data management, epidemiological and transcriptome cores of the TMRC program. 2. To coordinate the quarterly meeting of the project PIs of the and the meeting of the PIs and Co-PIs during the annual meeting of the American Society of Tropical Medicine and Hygiene. 3. To provide financial oversight of grant accounting at UFBA, UFRN, UVA, Cornell University and the University of lowa. 4. To facilitate the purchase of supplies and equipment for the projects and cores in Brazil and in the US. 5. To coordinate the annual TMRC meetings for the Brazilian TMRC investigators, as well as the collaborators and Advisory Committee members from the USA and Australia.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center (P50)
Project #
2P50AI030639-20
Application #
8304428
Study Section
Special Emphasis Panel (ZAI1-AWA-M (J1))
Project Start
Project End
2013-07-31
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
20
Fiscal Year
2012
Total Cost
$60,463
Indirect Cost
$4,479
Name
Federal University of Bahia
Department
Type
DUNS #
900845397
City
Salvador
State
Country
Brazil
Zip Code
40110-160
Silva, Silvana C; Guimarães, Luiz Henrique; Silva, Juliana A et al. (2018) Molecular epidemiology and in vitro evidence suggest that Leishmania braziliensis strain helps determine antimony response among American tegumenary leishmaniasis patients. Acta Trop 178:34-39
Sousa, Rosana; Andrade, Viviane M; Bair, Thomas et al. (2018) Early Suppression of Macrophage Gene Expression by Leishmania braziliensis. Front Microbiol 9:2464
Teixeira, D G; Monteiro, G R G; Martins, D R A et al. (2017) Comparative analyses of whole genome sequences of Leishmania infantum isolates from humans and dogs in northeastern Brazil. Int J Parasitol 47:655-665
Lima, Josivan Gomes; Nobrega, Lucia Helena C; Lima, Natalia Nobrega et al. (2017) Normal bone density and trabecular bone score, but high serum sclerostin in congenital generalized lipodystrophy. Bone 101:21-25
Lima, Ádila L M; de Lima, Iraci D; Coutinho, José F V et al. (2017) Changing epidemiology of visceral leishmaniasis in northeastern Brazil: a 25-year follow-up of an urban outbreak. Trans R Soc Trop Med Hyg 111:440-447
Kelly, Patrick H; Bahr, Sarah M; Serafim, Tiago D et al. (2017) The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum. MBio 8:
Gimblet, Ciara; Meisel, Jacquelyn S; Loesche, Michael A et al. (2017) Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation. Cell Host Microbe 22:13-24.e4
Almeida, Lucas; Silva, Juliana A; Andrade, Viviane M et al. (2017) Analysis of expression of FLI1 and MMP1 in American cutaneous leishmaniasis caused by Leishmania braziliensis infection. Infect Genet Evol 49:212-220
Weirather, Jason L; Duggal, Priya; Nascimento, Eliana L et al. (2017) Comprehensive candidate gene analysis for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil. Ann Hum Genet 81:41-48
Novais, Fernanda O; Carvalho, Augusto M; Clark, Megan L et al. (2017) CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1? production. PLoS Pathog 13:e1006196

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