The Administrative Core (Core A) is responsible for the administrative support of all UAB/UMN SPORE in Pancreatic Cancer Projects, Cores and Career Development and Developmental Research Programs, including planning and monitoring of scientific activities, providing scientific direction, ensuring a translational research emphasis, and integrating the Projects, Cores and Career Development and Developmental Research Programs, including collaborations with other Pancreatic SPORES. The Administrative Core provides fiscal oversight including 1) employment of key personnel to ensure cost effective and efficient use of resources and 2) utilization of SPORE flexibility to reallocate funds depending on the degree to which the individual Projects and Cores of the Pancreatic Cancer SPORE are successful in meeting their performance benchmarks, which allows the Administrative Core to take advantage of new scientific opportunities as well as to remedy deficiencies. The Administrative Core provides a vital link and coordination between investigators and the Pancreatic Cancer SPORE internal and external advisors, as well as NCI program staff, and assumes responsibility for the preparation of all required reports and assurances. The Administrative Core also manages a registered Pancreatic Cancer SPORE website and contributes to the Cancer Center Magazine, which serves the UAB community and the friends and supporters of the UAB CCC, and to the UMN CCC quarterly magazine and the UMN Medical School Medical Bulletin. The Administrative Core supports all ofthe SPORE Projects with planning, monitoring and the achievement of the scientific objectives of each SPORE Project/Core facility.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Alabama Birmingham
United States
Zip Code
Tiriac, Hervé; Belleau, Pascal; Engle, Dannielle D et al. (2018) Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer. Cancer Discov 8:1112-1129
Tiriac, Herve; Bucobo, Juan Carlos; Tzimas, Demetrios et al. (2018) Successful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized cancer treatment. Gastrointest Endosc 87:1474-1480
Carlson, Marjorie; Watson, Adrienne L; Anderson, Leah et al. (2017) Multiphoton fluorescence lifetime imaging of chemotherapy distribution in solid tumors. J Biomed Opt 22:1-9
Öhlund, Daniel; Handly-Santana, Abram; Biffi, Giulia et al. (2017) Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med 214:579-596
Zhong, Yi; Macgregor-Das, Anne; Saunders, Tyler et al. (2017) Mutant p53 Together with TGF? Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer. Clin Cancer Res 23:1607-1620
Contreras, Carlo M; Lin, Chee Paul; Oster, Robert A et al. (2017) Increased pancreatic cancer survival with greater lymph node retrieval in the National Cancer Data Base. Am J Surg 214:442-449
Roe, Jae-Seok; Hwang, Chang-Il; Somerville, Tim D D et al. (2017) Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell 170:875-888.e20
Chio, Iok In Christine; Tuveson, David A (2017) ROS in Cancer: The Burning Question. Trends Mol Med 23:411-429
Li, Yonghe; Oliver, Patsy G; Lu, Wenyan et al. (2017) SRI36160 is a specific inhibitor of Wnt/?-catenin signaling in human pancreatic and colorectal cancer cells. Cancer Lett 389:41-48
Feigin, Michael E; Garvin, Tyler; Bailey, Peter et al. (2017) Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma. Nat Genet 49:825-833

Showing the most recent 10 out of 173 publications