The vision of our JHU ICMIC Career Developmental Component (CDC) is to generate a small select group of scientists to provide academic scientific leadership in molecular imaging of cancer in the 21st century. The career trajectories of our awardees from the previous funding period are proof that this vision was, and will continue to be, successfully realized. We have established a training environment enriched with a multidisciplinary group of mentors with outstanding skills ranging from imaging, imaging probe design, visualization, oncology, to molecular biology and pathology. These human resources and the instrumentation and facilities continue to offer unprecedented word-class opportunities for the application of novel imaging approaches to understanding cancer.
The specific aim of the CDC is to provide formal training as well as inculcate independent research activities in a flourishing research environment. Targeted recruitment of women and minorities will be carried out including summer training for minority students. We will advertise one award every year at the postdoctoral or junior faculty level. Our purpose is to create a transition environment within the backdrop of the JHU ICMIC for the trainee to acquire the necessary skills and expertise to become an investigator capable of establishing an independent multidisciplinary imaging research program. To do this it is important to provide the necessary mentoring, and create independent thinkers capable of making decisions regarding the direction of their project, and the utilization of their resources. Providing trainees with their own independent budget that pays for percent effort, research supplies, and other expenses is highly motivational, and inculcates confidence and independence. Each trainee will be assigned a CDC sponsor from the CDC Faculty who will monitor and facilitate their training progress, and assist in the selection of a research mentor from the JHU ICMIC Faculty to perform ICMIC related research. Trainees will also be required to attend formal courses and training to complement their existing background and expertise. This will result in the generation of outstanding scientists with a well-rounded training in imaging, oncology and molecular biology.

Public Health Relevance

The CDC component of the JHU ICMIC Program is our investment in the future of molecular imaging in cancer. We hope that by recruiting and training the future leaders in the field, we will significantly advance the field of molecular imaging and its future impact in cancer discovery and treatment.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA103175-09
Application #
8728587
Study Section
Special Emphasis Panel (ZCA1-SRLB-9)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
9
Fiscal Year
2014
Total Cost
$130,592
Indirect Cost
$47,008
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Penet, Marie-France; Shah, Tariq; Bharti, Santosh et al. (2015) Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism. Clin Cancer Res 21:386-95
Ahn, Eun Hyun; Kim, Younghoon; Kshitiz et al. (2014) Spatial control of adult stem cell fate using nanotopographic cues. Biomaterials 35:2401-10
El Khouli, Riham H; Macura, Katarzyna J; Kamel, Ihab R et al. (2014) The effects of applying breast compression in dynamic contrast material-enhanced MR imaging. Radiology 272:79-90
Nimmagadda, Sridhar; Pullambhatla, Mrudula; Lisok, Ala et al. (2014) Imaging Axl expression in pancreatic and prostate cancer xenografts. Biochem Biophys Res Commun 443:635-40
Yadav, Nirbhay N; Xu, Jiadi; Bar-Shir, Amnon et al. (2014) Natural D-glucose as a biodegradable MRI relaxation agent. Magn Reson Med 72:823-8
Gadiya, Mayur; Mori, Noriko; Cao, Maria D et al. (2014) Phospholipase D1 and choline kinase-? are interactive targets in breast cancer. Cancer Biol Ther 15:593-601
Shamir, Eliah R; Pappalardo, Elisa; Jorgens, Danielle M et al. (2014) Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol 204:839-56
Huang, Peng; Ou, Ai-hua; Piantadosi, Steven et al. (2014) Formulating appropriate statistical hypotheses for treatment comparison in clinical trial design and analysis. Contemp Clin Trials 39:294-302
Subhawong, Ty K; Jacobs, Michael A; Fayad, Laura M (2014) Insights into quantitative diffusion-weighted MRI for musculoskeletal tumor imaging. AJR Am J Roentgenol 203:560-72
Zhu, Wenlian; Kato, Yoshinori; Artemov, Dmitri (2014) Water exchange-minimizing DCE-MRI protocol to detect changes in tumor vascular parameters: effect of bevacizumab/paclitaxel combination therapy. MAGMA 27:161-70

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