The vision of our JHU ICMIC Career Developmental Component (CDC) is to generate a small select group of scientists to provide academic scientific leadership in molecular imaging of cancer in the 21st century. The career trajectories of our awardees from the previous funding period are proof that this vision was, and will continue to be, successfully realized. We have established a training environment enriched with a multidisciplinary group of mentors with outstanding skills ranging from imaging, imaging probe design, visualization, oncology, to molecular biology and pathology. These human resources and the instrumentation and facilities continue to offer unprecedented word-class opportunities for the application of novel imaging approaches to understanding cancer.
The specific aim of the CDC is to provide formal training as well as inculcate independent research activities in a flourishing research environment. Targeted recruitment of women and minorities will be carried out including summer training for minority students. We will advertise one award every year at the postdoctoral or junior faculty level. Our purpose is to create a transition environment within the backdrop of the JHU ICMIC for the trainee to acquire the necessary skills and expertise to become an investigator capable of establishing an independent multidisciplinary imaging research program. To do this it is important to provide the necessary mentoring, and create independent thinkers capable of making decisions regarding the direction of their project, and the utilization of their resources. Providing trainees with their own independent budget that pays for percent effort, research supplies, and other expenses is highly motivational, and inculcates confidence and independence. Each trainee will be assigned a CDC sponsor from the CDC Faculty who will monitor and facilitate their training progress, and assist in the selection of a research mentor from the JHU ICMIC Faculty to perform ICMIC related research. Trainees will also be required to attend formal courses and training to complement their existing background and expertise. This will result in the generation of outstanding scientists with a well-rounded training in imaging, oncology and molecular biology.

Public Health Relevance

The CDC component of the JHU ICMIC Program is our investment in the future of molecular imaging in cancer. We hope that by recruiting and training the future leaders in the field, we will significantly advance the field of molecular imaging and its future impact in cancer discovery and treatment.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA103175-10
Application #
8906485
Study Section
Special Emphasis Panel (ZCA1-SRLB-9)
Project Start
Project End
2017-07-31
Budget Start
2015-08-01
Budget End
2016-07-31
Support Year
10
Fiscal Year
2015
Total Cost
$135,182
Indirect Cost
$48,615
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Nakamura, Hideki; Lee, Albert A; Afshar, Ali Sobhi et al. (2018) Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions. Nat Mater 17:79-89
Krishnamachary, Balaji; Danhier, Pierre; Kakkad, Samata et al. (2018) Hypoxia-Induced Reporter Genes with Different Half-Lives. Methods Mol Biol 1790:113-125
Plyku, Donika; Mena, Esther; Rowe, Steven P et al. (2018) Combined model-based and patient-specific dosimetry for 18F-DCFPyL, a PSMA-targeted PET agent. Eur J Nucl Med Mol Imaging 45:989-998
Pickett, Julie E; Thompson, John M; Sadowska, Agnieszka et al. (2018) Molecularly specific detection of bacterial lipoteichoic acid for diagnosis of prosthetic joint infection of the bone. Bone Res 6:13
Cheng, Menglin; Glunde, Kristine (2018) Magnetic Resonance Spectroscopy Studies of Mouse Models of Cancer. Methods Mol Biol 1718:331-345
van Zijl, Peter C M; Lam, Wilfred W; Xu, Jiadi et al. (2018) Magnetization Transfer Contrast and Chemical Exchange Saturation Transfer MRI. Features and analysis of the field-dependent saturation spectrum. Neuroimage 168:222-241
Chatterjee, Samit; Lesniak, Wojciech G; Miller, Michelle S et al. (2017) Rapid PD-L1 detection in tumors with PET using a highly specific peptide. Biochem Biophys Res Commun 483:258-263
Chen, Ying; Chatterjee, Samit; Lisok, Ala et al. (2017) A PSMA-targeted theranostic agent for photodynamic therapy. J Photochem Photobiol B 167:111-116
Lesniak, Wojciech G; Aboye, Teshome; Chatterjee, Samit et al. (2017) In vivo Evaluation of an Engineered Cyclotide as Specific CXCR4 Imaging Reagent. Chemistry 23:14469-14475
Xu, Jiadi; Chan, Kannie W Y; Xu, Xiang et al. (2017) On-resonance variable delay multipulse scheme for imaging of fast-exchanging protons and semisolid macromolecules. Magn Reson Med 77:730-739

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