The Clinical Core is the operational hub of the Center. It is integral to collecting the data necessary for satisfying centerwide aims as well as the specific aims of each research module. The Clinical Core also conducts the psychiatric diagnostic evaluations of all members of the nuclear family (N= 775 families) consisting of the proband father, his spouse, and has biological and stepchildren. Step-parents are also diagnostically evaluated. In addition, this Core performs medical and dental examinations of the children and administers the research protocols to each family member, including collection of biological specimens (blood, saliva, skin, urine) for timely distribution to various laboratories. The Clinical Core ensures compliance with the University of Pittsburgh IRB, HIPPA, and NIH regulations. While primarily responsible for operational support of the Center's scientific activities, faculty in this Core are also integrally involved in empirical research. Accordingly, recent publications have focused on diverse topics, including the role of orodental health on SUD development, suicidality, sexual behavior and STD's, mortality, and health and psychiatric comorbidity.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA005605-21
Application #
8377641
Study Section
Special Emphasis Panel (ZDA1-EXL-T)
Project Start
Project End
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
21
Fiscal Year
2012
Total Cost
$447,541
Indirect Cost
$129,096
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Cochran, Gerald; Gordon, Adam J; Field, Craig et al. (2016) Developing a framework of care for opioid medication misuse in community pharmacy. Res Social Adm Pharm 12:293-301
Babinski, Dara E; Pelham Jr, William E; Molina, Brooke S G et al. (2016) Maternal ADHD, Parenting, and Psychopathology Among Mothers of Adolescents With ADHD. J Atten Disord 20:458-68
Schwantes-An, Tae-Hwi; Zhang, Juan; Chen, Li-Shiun et al. (2016) Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behav Genet 46:151-69
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Rabinowitz, Jill A; Drabick, Deborah A G; Reynolds, Maureen D et al. (2016) Child Temperamental Flexibility Moderates the Relation between Positive Parenting and Adolescent Adjustment. J Appl Dev Psychol 43:43-53
Bastian, Jaime R; Chen, Huijun; Zhang, Hongfei et al. (2016) Dose-adjusted plasma concentrations of sublingual buprenorphine are lower during than after pregnancy. Am J Obstet Gynecol :

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