We seek to renew our psychotherapy research center dedicated to the development, evaluation and community application of psychotherapies for drug abuse. The organizing theme is psychotherapy development and empirical testing based on the Stage Model (Rounsaville, Carroll, & Onken, 2001) of psychotherapy research. The Center's goal is to catalyze the development of innovative drug abuse treatments from the point where they are merely """"""""good ideas"""""""" to one where they are capable of widespread use as empirically supported treatments (EST's). The process requires research as sequential, progressively demanding stages. Stage I consists of pilot testing, manual writing and training program development. Stage II consists of controlled efficacy trials. Stage III consists of studies to evaluate generalizability of efficacious treatments to general clinical practice. During the second 5 years of Center activities we have successfully conducted the 5 originally proposed component research projects, completed 11 pilot projects and guided 6 new Yale investigators to develop their first externally supported research projects on behavioral treatments. We have also served as a national resource for psychotherapy research by consulting on development of 35 funded projects outside Yale, overseeing manual guided training for 13 multi-site behavioral and / or pharmacotherapy efficacy trials, developing training packages to foster more widespread use of efficacious substance abuse treatments and providing consultation on issues related to behavioral therapies research to national organizations. During the renewal period, research will continue to be organized around the Stage Model with a CORE facility and 4 component projects. Core staff will provide scientific oversight, administration and technical assistance to center projects and also provide consultation and technology transfer services to investigators and clinicians at other sites. Two Stage I projects will develop new approaches: Contingency Management for Adolescent Smokers and Brief Drop-out Re-engagement Strategies. Two Stage II projects will evaluate efficacy of the following: Enhanced and attendance-based prize CM in community settings and Maximizing the Efficacy of CBT and Contingency Management.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
2P50DA009241-11
Application #
6764908
Study Section
Special Emphasis Panel (ZDA1-RXL-E (23))
Program Officer
Riddle, Melissa
Project Start
1997-07-01
Project End
2009-06-30
Budget Start
2004-09-10
Budget End
2005-06-30
Support Year
11
Fiscal Year
2004
Total Cost
$1,853,967
Indirect Cost
Name
Yale University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
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Rash, Carla J; Petry, Nancy M; Alessi, Sheila M (2018) A randomized trial of contingency management for smoking cessation in the homeless. Psychol Addict Behav 32:141-148
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Paris, Manuel; Silva, Michelle; AƱez-Nava, Luis et al. (2018) Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial. Am J Public Health 108:1535-1542
Carroll, Kathleen M; Nich, Charla; Frankforter, Tami L et al. (2018) Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug Alcohol Depend 192:264-270
DeVito, Elise E; Kiluk, Brian D; Nich, Charla et al. (2018) Drug Stroop: Mechanisms of response to computerized cognitive behavioral therapy for cocaine dependence in a randomized clinical trial. Drug Alcohol Depend 183:162-168
Petry, Nancy M; Alessi, Sheila M; Rash, Carla J et al. (2018) A randomized trial of contingency management reinforcing attendance at treatment: Do duration and timing of reinforcement matter? J Consult Clin Psychol 86:799-809

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