The Administrative Core will manage the overall operations of the center, and will be responsible for coordinating the activities of the various components to promote the cohesive functioning of the center as a whole. This will include monitoring progress on all projects, and scheduling the allocation of other core resources (Recruitment/Screening Core, Education Core), to ensure their efficient use while maintaining a steady demand on these resources. The administrative core will also monitor and control expenditures of all center projects as well as handle budget projections. In addition, this core will coordinate interactions with the Extemal Advisory Committee and the Data Safety Monitoring Board. Moreover, the Administrative Core will organize monthly meetings of the Executive Committee, consisting of Project Directors (PDs), Core Directors (CDs), and other key center personnel. These meetings will foster communication among the PDs and CDs and facilitate key decision making activities to guide the center's progress to achieve our scientific and training objectives.
Cigarette smoking is the leading preventable cause of disease and death in the U.S. This health burden can be reduced substantially by quitting smoking, and yet current smoking cessation treatments have only limited effectiveness. By coordinating the activities of the center, this core will promote the goals of developing more efficacious smoking cessation treatments and communicating this knowledge to the community. This in turn will have a major positive impact on public health.
|Rezvani, Amir H; Cauley, Marty C; Levin, Edward D (2014) Lorcaserin, a selective 5-HT(2C) receptor agonist, decreases alcohol intake in female alcohol preferring rats. Pharmacol Biochem Behav 125:8-14|
|Hall, Brandon J; Wells, Corinne; Allenby, Cheyenne et al. (2014) Differential effects of non-nicotine tobacco constituent compounds on nicotine self-administration in rats. Pharmacol Biochem Behav 120:103-8|
|Levin, Edward D; Hao, Ian; Burke, Dennis A et al. (2014) Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats. J Psychopharmacol 28:915-22|
|Levin, Edward D (2013) Complex relationships of nicotinic receptor actions and cognitive functions. Biochem Pharmacol 86:1145-52|
|Bough, K J; Lerman, C; Rose, J E et al. (2013) Biomarkers for smoking cessation. Clin Pharmacol Ther 93:526-38|
|Kutlu, Munir G; Burke, Dennis; Slade, Susan et al. (2013) Role of insular cortex Dýýý and Dýýý dopamine receptors in nicotine self-administration in rats. Behav Brain Res 256:273-8|
|Rezvani, Amir H; Sexton, Hannah G; Johnson, Joshua et al. (2013) Effects of caffeine on alcohol consumption and nicotine self-administration in rats. Alcohol Clin Exp Res 37:1609-17|
|Hall, F Scott; Markou, Athina; Levin, Edward D et al. (2012) Mouse models for studying genetic influences on factors determining smoking cessation success in humans. Ann N Y Acad Sci 1248:39-70|
|Levin, Edward D; Slade, Susan; Wells, Corinne et al. (2011) D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response. Pharmacol Biochem Behav 98:210-4|
|Levin, Edward D; Johnson, Joshua E; Slade, Susan et al. (2011) Lorcaserin, a 5-HT2C agonist, decreases nicotine self-administration in female rats. J Pharmacol Exp Ther 338:890-6|