This proposal, as part of the Center theme to translate scientific findings to guide the development of resources and tools for parents, is aimed at parents with a teenager who is already starting to use drugs. The proposed research will test a new, innovative version of a brief intervention. This program will be home based rather than implemented by a counselor in a clinical setting. Consistent with the Center translational strategy, this proposed study is stage I to stage II research. The stage I activities will involve manual development, parent training development, and a small feasibility study;Stage II involves a formal efficacy randomized controlled trial. Subsequent to the efficacy trial, additional translational work by the Center's Communications Unit (Parent Advisory Board and the Partnership for a Drug Free America) will promote the product's transportability into the community. The study's potential to develop a user-friendly and scientifically sound parent intervention program benefits from being part ofthe proposed Center. The study's specific aims are the following:
Aim 1. Design a new, parent-led and home based brief intervention to address mild-to-moderate drug abuse in the teenage child (age range 12-15).
Aim 2. Evaluate the efficacy of the parent intervenfion using a random controlled trial. Two samples, 110 families each, will participate in the randomized controlled trial. Families will be randomly assigned to either an intervention or control conditions. Data to quantify intervention effects will be obtained by interviewing adolescents and target parent at multiple time points (baseline and 1-, 3-, 6- and 12-months post baseline). We hypothesize that the home based intervention will be superior to a control condition.
Aim 3. To examine hypothesized mediating mechanisms that contribute to post-intervention drug use behaviors in the adolescent. Response to the intervention by the adolescent will be mediated by motivation, cognitions, problem solving, peer drug use, parenting skills and parent self-efficacy.

Public Health Relevance

Brief interventions (Bl) are a promising model for adolescents who abuse drugs but are not dependent, and a home-based approach has the potential to be effective because parents have an ongoing opportunity to promote changes in their drug-abusing teenager. Also, the proposed study fills an important service gap because Bis for early-stage drug abuse are rarely an option in the current drug treatment environment.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Specialized Center (P50)
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Special Emphasis Panel (ZDA1-EXL-T)
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Treatment Research Institute, Inc. (TRI)
United States
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Winters, Ken C; Lee, Susanne; Botzet, Andria et al. (2014) One-year outcomes and mediators of a brief intervention for drug abusing adolescents. Psychol Addict Behav 28:464-74
Hudson, Clifton R; Kirby, Kimberly C; Clements, Nicolle T et al. (2014) Social adjustment of women with and without a substance-abusing partner. J Psychoactive Drugs 46:106-13
Kaynak, Övgü; Winters, Ken C; Cacciola, John et al. (2014) Providing alcohol for underage youth: what messages should we be sending parents? J Stud Alcohol Drugs 75:590-605
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Kaynak, Ovgu; Meyers, Kathleen; Caldeira, Kimberly M et al. (2013) Relationships among parental monitoring and sensation seeking on the development of substance use disorder among college students. Addict Behav 38:1457-63
Arria, Amelia M; Wilcox, Holly C; Caldeira, Kimberly M et al. (2013) Dispelling the myth of "smart drugs": cannabis and alcohol use problems predict nonmedical use of prescription stimulants for studying. Addict Behav 38:1643-50
Kirby, Kimberly C; Carpenedo, Carolyn M; Dugosh, Karen L et al. (2013) Randomized clinical trial examining duration of voucher-based reinforcement therapy for cocaine abstinence. Drug Alcohol Depend 132:639-45
Arria, Amelia M; Garnier-Dykstra, Laura M; Cook, Emily T et al. (2013) Drug use patterns in young adulthood and post-college employment. Drug Alcohol Depend 127:23-30
Winters, Ken C (2013) Advances in the science of adolescent drug involvement: implications for assessment and diagnosis - experience from the United States. Curr Opin Psychiatry 26:318-24

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