The purpose of the Translational Drug Abuse Prevention Center (TDAP) is to conduct a program of innovative and thematically-integrated research spanning basic science, efficacy and effectiveness trials, and implementation work focused on drug abuse prevention in the child welfare system (CWS). Within that Center, the Administrative Core serves vital functions of organization, training, and dissemination. Our previous work has included basic scientific and neurobiological investigations of risk factors for drug abuse in the CWS, as well as randomized efficacy and effectiveness trials of preventive interventions, and most recently, investigations into the domain of Implementation science. The proposed PSO will further expand the breadth, reach, and focus of our work to inform science, practice, and policy regarding drug abuse prevention in the CWS into areas that include implementation science, gender-related risks for drug abuse and HIV-risk behaviors, and social-context based neurocognitive processes Involved In initiation and escalation of drug use in adolescence. Additionally, we will work to make critical breakthroughs in integrating multiple methodologies and statistical techniques into drug abuse prevention research in the CWS. Finally, the Center will provide essential mentoring and training that will allow the early career and minority scientists within the Centerto become nationally-recognized leaders in the field. The achievement of these aims is dependent upon an underlying infrastructure that promotes collaboration, communication, and integration of the three Research Components and Cores within the Center. The Administrative Core will provide this critical infrastructure. The Core will also support and monitor the mentorship and training activities within the Center in collaboration with the other two Cores. Additionally, the Core will facilitate and organize efforts to disseminate the Information gained from Center activities to research and practice communities, and to gather information from those communities about potentially impactful future research and intervention avenues.

Public Health Relevance

Children in the CWS are among the most disadvantaged individuals in America, with elevated drug use, delinquency, and HIV-risk behaviors. Evidence-based interventions for CWS-involved families are rarely implemented into routine CWS practice. The proposed Center would provide a national resource in drug abuse prevention research, with the ultimate goal of reducing drug use and related outcomes for CWS youth,

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Specialized Center (P50)
Project #
Application #
Study Section
Special Emphasis Panel (ZDA1-EXL-T)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Oregon Social Learning Center, Inc.
United States
Zip Code
Clark, Miriam; Buchanan, Rohanna; Kovensky, Rachel et al. (2018) Partner influences on young women's risky drug and sexual behavior. Reprod Health 15:156
Vijayakumar, Nandita; Op de Macks, Zdena; Shirtcliff, Elizabeth A et al. (2018) Puberty and the human brain: Insights into adolescent development. Neurosci Biobehav Rev 92:417-436
Gewirtz, Abigail H; DeGarmo, David S; Zamir, Osnat (2018) Testing a Military Family Stress Model. Fam Process 57:415-431
Roos, Leslie E; Beauchamp, Kathryn G; Giuliano, Ryan et al. (2018) Children's biological responsivity to acute stress predicts concurrent cognitive performance. Stress 21:347-354
Berkman, Elliot T (2018) Value-based choice: An integrative, neuroscience-informed model of health goals. Psychol Health 33:40-57
Clark, Miriam; Buchanan, Rohanna; Leve, Leslie D (2018) Young Women's Perspectives of Their Adolescent Treatment Programs: A Qualitative Study. Int J Environ Res Public Health 15:
Leve, Leslie D; Neiderhiser, Jenae M; Harold, Gordon T et al. (2018) Naturalistic Experimental Designs as Tools for Understanding the Role of Genes and the Environment in Prevention Research. Prev Sci 19:68-78
Horn, Sarah R; Roos, Leslie E; Berkman, Elliot T et al. (2018) Neuroendocrine and immune pathways from pre- and perinatal stress to substance abuse. Neurobiol Stress 9:140-150
DeStasio, Krista L; Hill, Anne P; Berkman, Elliot T (2018) Efficacy of an SMS-Based Smoking Intervention Using Message Self-Authorship: A Pilot Study. J Smok Cessat 13:55-58
Beauchamp, Kathryn G; Shaffer, Kelsey A; Fisher, Philip A et al. (2018) Brief, computerized inhibitory control training to leverage adolescent neural plasticity: A pilot effectiveness trial. Appl Neuropsychol Child :1-17

Showing the most recent 10 out of 112 publications