This is a continuation of a program for the study of clinical, neurolinguistic, and neuroanatomic aspects of aphasia. The long-term objectives are to advance the understanding of the mechanisms of normal language and their neural basis so as to develop a coherent view of how the symptomatology of aphasia relates to the injury of particular brain structures and the consequent modification of linguistic and cognitive capacities. A concurrent goal is to apply developing theoretical insights to a rationally based diagnostic assessment and treatment of aphasia. Specific goals in the proposed project period and methods of accomplishing them are: 1. to investigate disorders of sentence comprehension and sentence production in terms of the explanatory power of specific cognitive and linguistic principles. 2. to study word production and word comprehension with techniques that probe the unfolding of these processes and their breakdown in real time. 3. to compare the comprehension of discourse -- particularly pragmatic aspects -- in aphasic and right brain damaged subjects. 4. to examine the cognitive basis for the success of global aphasics in mastering a nonverbal computerized communication system. 5. to study changes in attentional functions, associated with frontal lobe lesions and how they modify aphasic symptoms due to left temporal lobe lesions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Specialized Center (P50)
Project #
5P50DC000081-33
Application #
2608229
Study Section
Communication Disorders Review Committee (CDRC)
Project Start
1977-12-01
Project End
2000-11-30
Budget Start
1997-12-01
Budget End
1998-11-30
Support Year
33
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Boston University
Department
Neurology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
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