The object of this research proposal is the improvement of the care of burned patients. We believe that the most rational way to achieve this end is to focus our research efforts along critical problem areas in the treatment of burned patients. The overall approach is a coordinated multidisciplinary effort involving clinicians and basic scientists carrying out clinical studies correlated with multidisciplinary-based laboratory investigations, each examining the same traumatized subject extending from in vivo studies to organ perfusion, organ culture, and cellular investigations. The areas that have been identified for investigation are: 1) gastrointestinal function after thermal injury, 2) effect of burn injury on substrate metabolism, 3) burn injury extension, 4) burn injury - protein, amino acid and energy metabolism, 5) molecular pathology of healing and burn scar, and 6) burn trauma cellular endocrine response.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM021700-11
Application #
3106022
Study Section
(SRC)
Project Start
1977-12-01
Project End
1987-11-30
Budget Start
1984-12-01
Budget End
1987-11-30
Support Year
11
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
Shank, Erik S; Martyn, Jeevendra A; Donelan, Mathias B et al. (2016) Ultrasound-Guided Regional Anesthesia for Pediatric Burn Reconstructive Surgery: A Prospective Study. J Burn Care Res 37:e213-7
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