The Administrative Core will organize and supervise all administrative aspects of the Program, including organizing and documenting the weekly meetings, the monthly meetings of the Project and Core Leaders and Co-lnvestigators as well as the regularly scheduled meetings of the Internal and External Advisory Boards. This Core will provide financial oversight of all aspects of the Program to ensure that all federal regulations regarding the use of research funds are followed. The Administrative Core will also be responsible for the timely delivery of progress reports and other documentation to the NIH. The Administrative Core will be located in an office adjacent to the laboratory complex and the office of Dr. Banerjee, who is the Principal Investigator for this Program. This Core will also support the efforts of all of the Project Investigators in the preparation of data and manuscripts for presentation and publication. The Administrative Core will ensure that regular communication, synergy, and interaction among the investigators is maintained. The core will coordinate the Outreach efforts of this Center. Each of the three institutions involved, Denver Health (trauma) Belle Bonfils Blood Center (transfusion) and the University of Colorado (basic sciences) offer advantageous environments to disseminate Trauma research to faculty, residents and the public.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM049222-19
Application #
8499331
Study Section
Special Emphasis Panel (ZGM1-PPBC-5)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
19
Fiscal Year
2013
Total Cost
$192,572
Indirect Cost
$66,707
Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Lawson, Peter J; Moore, Hunter B; Moore, Ernest E et al. (2017) Preoperative thrombelastography maximum amplitude predicts massive transfusion in liver transplantation. J Surg Res 220:171-175
Moore, Frederick A; Moore, Ernest E; Billiar, Timothy R et al. (2017) The role of NIGMS P50 sponsored team science in our understanding of multiple organ failure. J Trauma Acute Care Surg 83:520-531
Stettler, Gregory R; Moore, Ernest E; Moore, Hunter B et al. (2017) Platelet adenosine diphosphate receptor inhibition provides no advantage in predicting need for platelet transfusion or massive transfusion. Surgery 162:1286-1294
Moore, Hunter B; Moore, Ernest E; Chapman, Michael P et al. (2017) Viscoelastic Tissue Plasminogen Activator Challenge Predicts Massive Transfusion in 15 Minutes. J Am Coll Surg 225:138-147
Clendenen, Nathan; Nunns, Geoffrey R; Moore, Ernest E et al. (2017) Hemorrhagic shock and tissue injury drive distinct plasma metabolome derangements in swine. J Trauma Acute Care Surg 83:635-642
Sauaia, Angela; Moore, Frederick A; Moore, Ernest E (2017) Postinjury Inflammation and Organ Dysfunction. Crit Care Clin 33:167-191
Slaughter, Anne L; Nunns, Geoffrey R; D'Alessandro, Angelo et al. (2017) The Metabolopathy of Tissue Injury, Hemorrhagic Shock and Resuscitation in a Rat Model. Shock :
Silliman, Christopher C; Kelher, Marguerite R; Khan, Samina Y et al. (2017) Supernatants and lipids from stored red blood cells activate pulmonary microvascular endothelium through the BLT2 receptor and protein kinase C activation. Transfusion 57:2690-2700
Reisz, Julie A; Slaughter, Anne L; Culp-Hill, Rachel et al. (2017) Red blood cells in hemorrhagic shock: a critical role for glutaminolysis in fueling alanine transamination in rats. Blood Adv 1:1296-1305
D?Alessandro, Angelo; Moore, Hunter B; Moore, Ernest E et al. (2017) Plasma succinate is a predictor of mortality in critically injured patients. J Trauma Acute Care Surg 83:491-495

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