Modeling and Informatics (0.9 FTE) The modeling and informatics core has three missions (i) it provide the electronic infrastructure for the CDP Web, CDP Wiki and its high performance computing and storage systems (ii) it develops new informatics technologies and oversees development of SB-Pipeline (iii) it trains CDP members in general on various types of software and assists with computer-intensive live-cell imaging. Jeremy Muhlich is primarily active as a programmer and was first author on the recently-submitted SB-Wiki paper, attesting to his high research productivity. Jay Copeland is involved in building and maintaining infrastructure and is our primary contact with Harvard and MIT systems administrators. Jay also runs the AV services, Web sites, on-line registration etc for conferences and meetings. Finally, Jay is the first point of contact in CDP for our software vendors and oversees all of its optical equipment (in addition to being a systems administrator, Jay is an experienced microscopist).

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM068762-10
Application #
8381016
Study Section
Special Emphasis Panel (ZGM1-CBCB-4)
Project Start
Project End
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
10
Fiscal Year
2012
Total Cost
$188,741
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Jaqaman, Khuloud; Galbraith, James A; Davidson, Michael W et al. (2016) Changes in single-molecule integrin dynamics linked to local cellular behavior. Mol Biol Cell 27:1561-9
Qian, Wen-Jian; Park, Jung-Eun; Grant, Robert et al. (2015) Neighbor-directed histidine N (Ï„)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles. Biopolymers 104:663-73
Hsu, Albert T; Barrett, Christopher D; DeBusk, George M et al. (2015) Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome. Shock 44:128-36
Ramírez-Gordillo, Daniel; Powers, TuShun R; van Velkinburgh, Jennifer C et al. (2015) RNA-Seq and microarray analysis of the Xenopus inner ear transcriptome discloses orthologous OMIM(®) genes for hereditary disorders of hearing and balance. BMC Res Notes 8:691
Landry, Benjamin D; Clarke, David C; Lee, Michael J (2015) Studying Cellular Signal Transduction with OMIC Technologies. J Mol Biol 427:3416-40
Dutta, Sanjib; Ryan, Jeremy; Chen, T Scott et al. (2015) Potent and specific peptide inhibitors of human pro-survival protein Bcl-xL. J Mol Biol 427:1241-53
Sarkar, Aniruddh; Kolitz, Sarah; Lauffenburger, Douglas A et al. (2014) Microfluidic probe for single-cell analysis in adherent tissue culture. Nat Commun 5:3421
Ebrahimkhani, Mohammad R; Neiman, Jaclyn A Shepard; Raredon, Micha Sam B et al. (2014) Bioreactor technologies to support liver function in vitro. Adv Drug Deliv Rev 69-70:132-57
Kallenberger, Stefan M; Beaudouin, Joël; Claus, Juliane et al. (2014) Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis. Sci Signal 7:ra23
Bryan, Andrea K; Hecht, Vivian C; Shen, Wenjiang et al. (2014) Measuring single cell mass, volume, and density with dual suspended microchannel resonators. Lab Chip 14:569-76

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