METABOLOMICS CORE FACILITY (NEW) The Metabolomics Core Facility provides worid-dass capabilities in quantitation of small molecule metabolites through LC-MS/MS. It has special expertise in quantitation of metabolites from cultured cells, and is a leader in probing metabolic fluxes from cultured cells using isotopic tracers. Users of the facility include members of the Center of Quantitative Biology at Princeton and a diversity of national and international scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM071508-10
Application #
8534156
Study Section
Special Emphasis Panel (ZGM1-CBCB-4)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
10
Fiscal Year
2013
Total Cost
$189,539
Indirect Cost
$72,109
Name
Princeton University
Department
Type
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544
Zhou, Jian; Troyanskaya, Olga G (2016) Probabilistic modelling of chromatin code landscape reveals functional diversity of enhancer-like chromatin states. Nat Commun 7:10528
Cobbold, Simon A; Santos, Joana M; Ochoa, Alejandro et al. (2016) Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite. Sci Rep 6:19722
Cobbold, Simon A; Llinás, Manuel; Kirk, Kiaran (2016) Sequestration and metabolism of host cell arginine by the intraerythrocytic malaria parasite Plasmodium falciparum. Cell Microbiol 18:820-30
Berman, Gordon J; Bialek, William; Shaevitz, Joshua W (2016) Predictability and hierarchy in Drosophila behavior. Proc Natl Acad Sci U S A 113:11943-11948
Kamphorst, Jurre J; Nofal, Michel; Commisso, Cosimo et al. (2015) Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Res 75:544-53
Bothma, Jacques P; Garcia, Hernan G; Ng, Samuel et al. (2015) Enhancer additivity and non-additivity are determined by enhancer strength in the Drosophila embryo. Elife 4:
Purdy, John G; Shenk, Thomas; Rabinowitz, Joshua D (2015) Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Rep 10:1375-85
Fan, Jing; Teng, Xin; Liu, Ling et al. (2015) Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate. ACS Chem Biol 10:510-6
Haye, Joanna E; Gammie, Alison E (2015) The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis. PLoS Genet 11:e1005719
Parsons, Lance R; Tafuri, Yolanda R; Shreve, Jacob T et al. (2015) Rapid genome assembly and comparison decode intrastrain variation in human alphaherpesviruses. MBio 6:

Showing the most recent 10 out of 429 publications