The continued success of a Systems Biology Center requires the continuous recruitment of new members, as well as the development of new imaging and modeling tools and expansion of our research portfolio. We foster these goals in part through a pilot project program to support innovative research that is clearly aligned with STMC goals. As described in the Administrative Core Management plan, both Full and Affiliate members of the STMC are eligible for these awards. Two pilot projects ($25,000 each) are proposed herein for year 6 of P50 funding (Year 1 of the competitive renewal period). We look forward to the successes of these talented young investigators and to promoting their career development. RFAs for future pilot projects will be announced annually on the STMC website.
This section outlines the work proposed by two young faculty, who will be awarded Pilot Projects during the first year of the competitive renewal period. In future years, RFAs for pilot projects will be announced on the STMC website and awarded after review and ranking by the STMC leadership committee.
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|Kerketta, Romica; HalÃ¡sz, ÃdÃ¡m M; Steinkamp, Mara P et al. (2016) Effect of Spatial Inhomogeneities on the Membrane Surface on Receptor Dimerization and Signal Initiation. Front Cell Dev Biol 4:81|
|Levin, Drew; Forrest, Stephanie; Banerjee, Soumya et al. (2016) A spatial model of the efficiency of T cell search in the influenza-infected lung. J Theor Biol 398:52-63|
|Winner, Kimberly R Kanigel; Steinkamp, Mara P; Lee, Rebecca J et al. (2016) Spatial Modeling of Drug Delivery Routes for Treatment of Disseminated Ovarian Cancer. Cancer Res 76:1320-34|
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|Marjon, K D; Termini, C M; Karlen, K L et al. (2016) Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherin. Oncogene 35:4132-40|
|Fricke, G Matthew; Letendre, Kenneth A; Moses, Melanie E et al. (2016) Persistence and Adaptation in Immunity: T Cells Balance the Extent and Thoroughness of Search. PLoS Comput Biol 12:e1004818|
|Lin, Jia; Wester, Michael J; Graus, Matthew S et al. (2016) Nanoscopic cell-wall architecture of an immunogenic ligand in Candida albicans during antifungal drug treatment. Mol Biol Cell 27:1002-14|
|Termini, Christina M; Lidke, Keith A; Gillette, Jennifer M (2016) Tetraspanin CD82 Regulates the Spatiotemporal Dynamics of PKCÎ± in Acute Myeloid Leukemia. Sci Rep 6:29859|
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