The continued success of a Systems Biology Center requires the continuous recruitment of new members, as well as the development of new imaging and modeling tools and expansion of our research portfolio. We foster these goals in part through a pilot project program to support innovative research that is clearly aligned with STMC goals. As described in the Administrative Core Management plan, both Full and Affiliate members of the STMC are eligible for these awards. Two pilot projects ($25,000 each) are proposed herein for year 6 of P50 funding (Year 1 of the competitive renewal period). We look forward to the successes of these talented young investigators and to promoting their career development. RFAs for future pilot projects will be announced annually on the STMC website.

Public Health Relevance

This section outlines the work proposed by two young faculty, who will be awarded Pilot Projects during the first year of the competitive renewal period. In future years, RFAs for pilot projects will be announced on the STMC website and awarded after review and ranking by the STMC leadership committee.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
2P50GM085273-06
Application #
8767026
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-07-31
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of New Mexico Health Sciences Center
Department
Type
DUNS #
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Hoard, Brittany; Jacobson, Bruna; Manavi, Kasra et al. (2016) Extending rule-based methods to model molecular geometry and 3D model resolution. BMC Syst Biol 10 Suppl 2:48
Kerketta, Romica; Halász, Ádám M; Steinkamp, Mara P et al. (2016) Effect of Spatial Inhomogeneities on the Membrane Surface on Receptor Dimerization and Signal Initiation. Front Cell Dev Biol 4:81
Levin, Drew; Forrest, Stephanie; Banerjee, Soumya et al. (2016) A spatial model of the efficiency of T cell search in the influenza-infected lung. J Theor Biol 398:52-63
Winner, Kimberly R Kanigel; Steinkamp, Mara P; Lee, Rebecca J et al. (2016) Spatial Modeling of Drug Delivery Routes for Treatment of Disseminated Ovarian Cancer. Cancer Res 76:1320-34
Meddens, Marjolein B M; Liu, Sheng; Finnegan, Patrick S et al. (2016) Single objective light-sheet microscopy for high-speed whole-cell 3D super-resolution. Biomed Opt Express 7:2219-36
Hansen, Scott G; Wu, Helen L; Burwitz, Benjamin J et al. (2016) Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E. Science 351:714-20
Marjon, K D; Termini, C M; Karlen, K L et al. (2016) Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherin. Oncogene 35:4132-40
Fricke, G Matthew; Letendre, Kenneth A; Moses, Melanie E et al. (2016) Persistence and Adaptation in Immunity: T Cells Balance the Extent and Thoroughness of Search. PLoS Comput Biol 12:e1004818
Lin, Jia; Wester, Michael J; Graus, Matthew S et al. (2016) Nanoscopic cell-wall architecture of an immunogenic ligand in Candida albicans during antifungal drug treatment. Mol Biol Cell 27:1002-14
Termini, Christina M; Lidke, Keith A; Gillette, Jennifer M (2016) Tetraspanin CD82 Regulates the Spatiotemporal Dynamics of PKCα in Acute Myeloid Leukemia. Sci Rep 6:29859

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