GENOMICS CORE AND HUB OF INNOVATION Mission Research Areas I and III will use massively-parallel sequencing to assay the richness of microbial communities and the response of fish hosts to those communities. The Genomics Core Facility will assist in library preparation and routine analysis of raw data to allow Center members to perform genomic assays quickly and with the highest possible quality.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM098911-03
Application #
8727615
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Oregon
Department
Type
DUNS #
City
Eugene
State
OR
Country
United States
Zip Code
97403
Parthasarathy, Raghuveer (2017) Monitoring microbial communities using light sheet fluorescence microscopy. Curr Opin Microbiol 43:31-37
Burns, Adam R; Guillemin, Karen (2017) The scales of the zebrafish: host-microbiota interactions from proteins to populations. Curr Opin Microbiol 38:137-141
Melancon, E; Gomez De La Torre Canny, S; Sichel, S et al. (2017) Best practices for germ-free derivation and gnotobiotic zebrafish husbandry. Methods Cell Biol 138:61-100
Jones, Tiffani Alvey; Hernandez, Diane Z; Wong, Zoƫ C et al. (2017) The bacterial virulence factor CagA induces microbial dysbiosis that contributes to excessive epithelial cell proliferation in the Drosophila gut. PLoS Pathog 13:e1006631
Stagaman, Keaton; Burns, Adam R; Guillemin, Karen et al. (2017) The role of adaptive immunity as an ecological filter on the gut microbiota in zebrafish. ISME J 11:1630-1639
Small, Clayton M; Milligan-Myhre, Kathryn; Bassham, Susan et al. (2017) Host Genotype and Microbiota Contribute Asymmetrically to Transcriptional Variation in the Threespine Stickleback Gut. Genome Biol Evol 9:504-520
Taormina, Michael J; Hay, Edouard A; Parthasarathy, Raghuveer (2017) Passive and Active Microrheology of the Intestinal Fluid of the Larval Zebrafish. Biophys J 113:957-965
Burns, A R; Watral, V; Sichel, S et al. (2017) Transmission of a common intestinal neoplasm in zebrafish by cohabitation. J Fish Dis :
Stephens, W Zac; Burns, Adam R; Stagaman, Keaton et al. (2016) The composition of the zebrafish intestinal microbial community varies across development. ISME J 10:644-54
Burns, Adam R; Stephens, W Zac; Stagaman, Keaton et al. (2016) Contribution of neutral processes to the assembly of gut microbial communities in the zebrafish over host development. ISME J 10:655-64

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