Core A. Administrative Core. The Administrative Core will serve to coordinate and support the activities of the Center in its entirety by facilitating communication between the PI, projects, cores, intemal advisors, external advisors, other Udall Centers, and the public. Salary support is requested for two individuals: The Center PI, Dr. Timothy Collier, and the Administrative Coordinator, Ms Michelle Gartland. Dr. Collier's effort will be devoted to oversight of the Core's activities, and participation in decision-making related to mechanisms for tracking progress and fiiture directions of the Center's scientific activities. This includesfrequentmeetings with Project Leaders and staff, annual meetings with intemal advisors and representatives of existing Udall Centers, bi-annual meetings with external advisors, and semi-annual revision of website content to communicate Center activities to the public. Day-to-day management of administrative activities (the real work) will be carried out by Ms. Michelle Gartland. Ms. Gartland has worked as an administrative/research assistant with Drs. Collier and Sortwell for five years. Her familiarity with both types of activities provides a significant advantage in execution of this role for the Center. In summary, the primary flmction of Core A is to enable communication. This will be achieved by 1) providing administrative support for the projects and cores, 2) scheduling and providing support for meetings between Center project leaders and intemal and external advisors, 3) facilitating travel and communication of data at annual Udall Centers meetings and meetings of national and international scientific societies, and 4) creating and maintaining a Center website. Ms. Gartland is experienced and talented in design of power point presentations and websites. These skills will enable center investigators to effectively communicate progress both to colleagues and to the public. The Center website will be the centerpiece of our group commitment to transparency in the use of Center funds as they apply to health and well-being of individuals with Parkinson's disease.

Public Health Relevance

Core A provides the administrative structure to promote the educational and informational mission of Udall Center activities for patients with Parkinson's disease and the Cincinnati community at large.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS058830-05
Application #
8532058
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
5
Fiscal Year
2013
Total Cost
$121,878
Indirect Cost
$61,448
Name
Michigan State University
Department
Type
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Polinski, Nicole K; Gombash, Sara E; Manfredsson, Fredric P et al. (2015) Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain. Neurobiol Aging 36:1110-20
Gombash, S E; Manfredsson, F P; Mandel, R J et al. (2014) Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways. Gene Ther 21:682-93
Hemmerle, A M; Dickerson, J W; Herman, J P et al. (2014) Stress exacerbates experimental Parkinson's disease. Mol Psychiatry 19:638-40
Levine, Nathan D; Rademacher, David J; Collier, Timothy J et al. (2013) Advances in thin tissue Golgi-Cox impregnation: fast, reliable methods for multi-assay analyses in rodent and non-human primate brain. J Neurosci Methods 213:214-27
Madhavan, Lalitha; Daley, Brian F; Sortwell, Caryl E et al. (2012) Endogenous neural precursors influence grafted neural stem cells and contribute to neuroprotection in the parkinsonian rat. Eur J Neurosci 35:883-95
Hemmerle, Ann M; Herman, James P; Seroogy, Kim B (2012) Stress, depression and Parkinson's disease. Exp Neurol 233:79-86
Gombash, Sara E; Lipton, Jack W; Collier, Timothy J et al. (2012) Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model. Mol Ther 20:544-54
Spieles-Engemann, Anne L; Steece-Collier, Kathy; Behbehani, Michael M et al. (2011) Subthalamic nucleus stimulation increases brain derived neurotrophic factor in the nigrostriatal system and primary motor cortex. J Parkinsons Dis 1:123-36
Kordower, Jeffrey H; Dodiya, Hemraj B; Kordower, Adam M et al. (2011) Transfer of host-derived * synuclein to grafted dopaminergic neurons in rat. Neurobiol Dis 43:552-7
Soderstrom, Katherine E; O'Malley, Jennifer A; Levine, Nathan D et al. (2010) Impact of dendritic spine preservation in medium spiny neurons on dopamine graft efficacy and the expression of dyskinesias in parkinsonian rats. Eur J Neurosci 31:478-90

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