The scientific focus of the Comprehensive Alcohol Research Center (CARC) at the LSU Health Sciences Center in New Orleans is to conduct cutting-edge basic research on alcohol and HIV that can be translated into effective community-based interventions. The oversight and operation of the CARC is conducted through the Administrative Core. The Administrative Core provides the organizational framework for the direction, management, and coordination of the CARC. Specifically, the Administrative Core;1) monitors the performance and productivity of the individual research components and cores;2) manages the budget and fiscal activities of the CARC;3) supervises the CARC personnel: and 4) plans and executes the educational, enrichment and dissemination functions of the Center. The Administrative Core also provides biostatistical support and is responsible for centralizing, coordinating, and integrating computer services for administrative and scientific components of the CARC. The Principal Investigator has responsibility for all CARC components and supervises their activities and receives valuable input from the Scientific Director, the Intramural Center Committee, and the Program Advisory Committee. The Administrative Core facilitates a synergistic and productive interaction among the participants which contributes substantially to the success of the CARC. Such interactions are a """"""""way of life"""""""" for the participating CARC scientists and include both formal and informal venues which provide ample opportunity for critique and cross-fertilization of ideas addressing the common goal of the health consequences of alcohol abuse. In addition to monitoring the progress and scientific productivity of the individual components of the CARC and fostering interdisciplinary cooperation, the Administrative Core manages the budget and fiscal activities of the Center. The Director of Education, Enrichment, and Dissemination Activities develops educational programs for the scientific and lay communities on the biomedical consequences of alcohol use and abuse. In summary, the Administrative Core is a mature, integrated organization with a successful record in developing a comprehensive, thematically focused research program that is both productive and cost-effective in an area of great clinical relevance.

Public Health Relevance

The Administrative Core is a mature, integrated organization that has developed a comprehensive research program on the effects of alcohol on HIV infection. HIV continues to be a major health problem in the U.S. with more than 40,000 estimated new infections annually. The CARC at LSUHSC is uniquely positioned to study the interactions of alcohol, HIV, and ART in the most widely accepted animal model of HIV infection and to translate these findings into community-based interventions.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Comprehensive Center (P60)
Project #
Application #
Study Section
Special Emphasis Panel (ZAA1-DD)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Louisiana State Univ Hsc New Orleans
New Orleans
United States
Zip Code
Merrill, Livia C; Jones, Christopher W; Drury, Stacy S et al. (2017) The differential impact of oxytocin receptor gene in violence-exposed boys and girls. Int J Dev Neurosci 59:60-67
Byerley, Lauri O; Samuelson, Derrick; Blanchard 4th, Eugene et al. (2017) Changes in the gut microbial communities following addition of walnuts to the diet. J Nutr Biochem 48:94-102
Ruan, Sanbao; Cai, Yang; Ramsay, Alistair J et al. (2017) B cell and antibody responses in mice induced by a putative cell surface peptidase of Pneumocystis murina protect against experimental infection. Vaccine 35:672-679
Samuelson, Derrick R; Shellito, Judd E; Maffei, Vincent J et al. (2017) Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae. PLoS Pathog 13:e1006426
Ng, Hang Pong; Jennings, Scott; Wang, Jack et al. (2017) Non-canonical Glucocorticoid Receptor Transactivation of gilz by Alcohol Suppresses Cell Inflammatory Response. Front Immunol 8:661
Duplanty, Anthony A; Simon, Liz; Molina, Patricia E (2017) Chronic Binge Alcohol-Induced Dysregulation of Mitochondrial-Related Genes in Skeletal Muscle of Simian Immunodeficiency Virus-Infected Rhesus Macaques at End-Stage Disease. Alcohol Alcohol 52:298-304
Simon, Liz; Siggins, Robert; Winsauer, Peter et al. (2017) Simian Immunodeficiency Virus Infection Increases Blood Ethanol Concentration Duration After Both Acute and Chronic Administration. AIDS Res Hum Retroviruses :
Goldsmith, Felicia; Guice, Justin; Page, Ryan et al. (2017) Obese ZDF rats fermented resistant starch with effects on gut microbiota but no reduction in abdominal fat. Mol Nutr Food Res 61:
Theall, Katherine P; Shirtcliff, Elizabeth A; Dismukes, Andrew R et al. (2017) Association Between Neighborhood Violence and Biological Stress in Children. JAMA Pediatr 171:53-60
Felker-Kantor, Erica; Wallace, Maeve; Theall, Katherine (2017) Living in violence: Neighborhood domestic violence and small for gestational age births. Health Place 46:130-136

Showing the most recent 10 out of 99 publications