Abstract

The Biostatistics Core will provide consultation and services to Center investigators in the areas of biostatistics, statistical genetics, quantitative modeling of biological and social-behavioral systems, scientific computing (including facilitating access to and use of InterNet resources), and data analysis. The core will function as a resource center for statistical and scientific computing on personal computers, high-end workstations, and InterNet resources. A special emphasis will be given to providing expertise in statistical genetics and facilitating collaborations between molecular geneticists, statistical genetics, and statisticians. A genetic epidemiology World Wide Web site with a focus on arthritis and related disorders will be maintained, and a series of informal seminars reviewing important articles in the genetic epidemiology of arthritis (held in conjunction with Core D --Molecular Biology) will be given.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
5P60AR040770-07
Application #
6268378
Study Section
Project Start
1998-03-01
Project End
1999-02-28
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
7
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Type
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Malcarne, Vanessa L; Hansdottir, Ingunn; McKinney, Ann et al. (2007) Medical signs and symptoms associated with disability, pain, and psychosocial adjustment in systemic sclerosis. J Rheumatol 34:359-67
Leake, John A D; Albani, Salvatore; Kao, Annie S et al. (2004) Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features. Pediatr Infect Dis J 23:756-64
Meyer, Markus; Belke, Darrell D; Trost, Susanne U et al. (2004) A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation. FASEB J 18:1312-4
Johnson, Kristen; Goding, James; Van Etten, Deborah et al. (2003) Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression. J Bone Miner Res 18:994-1004
Groessl, Erik J; Kaplan, Robert M; Cronan, Terry A (2003) Quality of well-being in older people with osteoarthritis. Arthritis Rheum 49:23-8
Kaplan, Robert M (2003) The significance of quality of life in health care. Qual Life Res 12 Suppl 1:3-16
Hessle, Lovisa; Johnson, Kristen A; Anderson, H Clarke et al. (2002) Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci U S A 99:9445-9
Kaplan, Robert M; Groessl, Erik J (2002) Applications of cost-effectiveness methodologies in behavioral medicine. J Consult Clin Psychol 70:482-93
Borevitz, Justin O; Maloof, Julin N; Lutes, Jason et al. (2002) Quantitative trait loci controlling light and hormone response in two accessions of Arabidopsis thaliana. Genetics 160:683-96
La Cava, Antonio; Massa, Margherita; Mendivil, Alberto et al. (2002) Genetic immunization maps T cell (auto)immune responses to self antigens homologous to exogenous proteins. Autoimmunity 35:105-10

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