Agency
National Institute of Health (NIH)
Type
Research Project (R01)
Project #
5R01AG007218-27
Application #
8665336
Study Section
No Study Section (in-house review) (NSS)
Program Officer
Finkelstein, David B
Project Start
Project End
Budget Start
Budget End
Support Year
27
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Texas Health Science Center
Department
Biology
Type
Schools of Medicine
DUNS #
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Sharma, Ramaswamy; Callaway, Danielle; Vanegas, Difernando et al. (2014) Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts. PLoS One 9:e93696
Lopez-Cruzan, Marisa; Herman, Brian (2013) Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species. Biogerontology 14:121-30
Ramanujan, V K; Jo, J A; Cantu, G et al. (2008) Spatially resolved fluorescence lifetime mapping of enzyme kinetics in living cells. J Microsc 230:329-38
Kalkonde, Yogeshwar V; Morgan, William W; Sigala, Jose et al. (2007) Chemokines in the MPTP model of Parkinson's disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration. Brain Res 1128:1-11
Ramanujan, V Krishnan; Herman, Brian A (2007) Aging process modulates nonlinear dynamics in liver cell metabolism. J Biol Chem 282:19217-26
Rodriguez-Enriquez, Sara; Kim, Insil; Currin, Robert T et al. (2006) Tracker dyes to probe mitochondrial autophagy (mitophagy) in rat hepatocytes. Autophagy 2:39-46
Ramanujan, V Krishnan; Biener, Gabriel; Herman, Brian A (2006) Scaling behavior in mitochondrial redox fluctuations. Biophys J 90:L70-2
Ramanujan, V Krishnan; Biener-Ramanujan, Eva; Armmer, Kinton et al. (2006) Spectral kinetics ratiometry: a simple approach for real-time monitoring of fluorophore distributions in living cells. Cytometry A 69:912-9
Elmore, Steven P; Nishimura, Yoshiya; Qian, Ting et al. (2004) Discrimination of depolarized from polarized mitochondria by confocal fluorescence resonance energy transfer. Arch Biochem Biophys 422:145-52
Kon, Kazuyoshi; Kim, Jae-Sung; Jaeschke, Hartmut et al. (2004) Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes. Hepatology 40:1170-9

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