Millions of older Americans experience cognitive declines as they age. Millions of older adults have sensory deficits that affect more than one sense. The focus to date on sensory decline, however, has been almost exclusively placed on simple clinical measures of threshold sensitivity in each sense. Based on our recently completed work, there is reason to believe that measures of temporal processing may be more sensitive to the effects of aging than measures of threshold sensitivity. In addition, our emerging model demonstrates that temporal processing in multiple senses is strongly associated with cognitive function (regardless of age). Our laboratory has developed an unprecedented cross-sectional data set on various aspects of temporal processing, from temporal acuity to temporal-order identification in three senses: hearing, vision, and touch. For the main baseline data set, data are available from 195 middle-aged and older adults tested on 34 sensory-processing measures using reliable, rigorous psychophysical methods. These data have permitted analysis and modeling of individual differences in performance within and across age groups;analyses that have heretofore not been possible. Age-group differences between young and older adults were also examined and were nearly universal among the set of 34 temporal-processing dependent measures included in our study. Although supportive of likely age-related changes in temporal processing, these changes require confirmation with longitudinal data on temporal processing. The gathering of such data from 195 middle-aged and older adults at 7 and 10 years following completion of the initial set of baseline measures represents the specific aim of the proposed project. In addition, there may be cognitive-health consequences for those middle-aged and older adults who exhibit poor temporal acuity and temporal-order identification in multiple senses. Individuals who exhibited this pattern of performance in the baseline cohort of 195 middle-aged and older adults, for example, had worse cognitive function. The greater the number of sensory processes impaired, the greater the cognitive decline. The longitudinal data to be gathered here will provide fundamental new knowledge about age-related sensory decline and also determine whether declines in sensory processing precede cognitive declines in older adults as hypothesized. If this hypothesis is confirmed, these findings could prove critical to the early diagnosis of cognitive decline in older adults and, ultimately, may lead to new approaches to intervention as well.

Public Health Relevance

Millions of older Americans have sensory deficits that affect more than one sense. There is reason to believe that measures of temporal processing from each sense may be sensitive to eventual cognitive declines accompanying aging. This project examines this issue longitudinally in middle-aged and older adults.

National Institute of Health (NIH)
Research Project (R01)
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Auditory System Study Section (AUD)
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Chen, Wen G
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Indiana University Bloomington
Other Health Professions
Schools of Arts and Sciences
United States
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Krull, Vidya; Humes, Larry E; Kidd, Gary R (2013) Reconstructing wholes from parts: effects of modality, age, and hearing loss on word recognition. Ear Hear 34:e14-23
Kidd, Gary R; Humes, Larry E (2012) Effects of age and hearing loss on the recognition of interrupted words in isolation and in sentences. J Acoust Soc Am 131:1434-48
Fogerty, Daniel; Humes, Larry E (2012) The role of vowel and consonant fundamental frequency, envelope, and temporal fine structure cues to the intelligibility of words and sentences. J Acoust Soc Am 131:1490-501
Fogerty, Daniel (2011) Perceptual weighting of individual and concurrent cues for sentence intelligibility: frequency, envelope, and fine structure. J Acoust Soc Am 129:977-88
Fogerty, Daniel (2011) Perceptual weighting of the envelope and fine structure across frequency bands for sentence intelligibility: effect of interruption at the syllabic-rate and periodic-rate of speech. J Acoust Soc Am 130:489-500
Fogerty, Daniel; Humes, Larry E (2010) Perceptual contributions to monosyllabic word intelligibility: segmental, lexical, and noise replacement factors. J Acoust Soc Am 128:3114-25
Wang, Xin; Humes, Larry E (2010) Factors influencing recognition of interrupted speech. J Acoust Soc Am 128:2100-11
Humes, Larry E; Burk, Matthew H; Strauser, Lauren E et al. (2009) Development and efficacy of a frequent-word auditory training protocol for older adults with impaired hearing. Ear Hear 30:613-27
Humes, Larry E; Coughlin, Maureen (2009) Aided speech-identification performance in single-talker competition by older adults with impaired hearing. Scand J Psychol 50:485-94
Shrivastav, Mini N; Humes, Larry E; Aylsworth, Lacy (2008) Temporal order discrimination of tonal sequences by younger and older adults: the role of duration and rate. J Acoust Soc Am 124:462-71

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