Our proposed study addresses the Program Announcement entitled 'Research on Mind-Body Interactions and Health' (PA-07-046). Specifically, we address the National Institute on Aging (NIA) interest in exploring associations between psychological well-being and functional ability in older adults hospitalized for acute illness.
The Specific Aims of the proposed application are to: 1. Examine change in functional status during hospitalization and up to one-year post hospital discharge. Functional status will be assessed by a battery of measures (a 4 meter walk, a test of grip strength, knee extensor strength and seven activities of daily living (ADLs)) at 5 time points: within 24 hours of hospital admission and discharge, and 1, 6 and 12 months post discharge. 2. Examine direct and indirect associations between psychological well-being and functional status during hospitalization and up to one-year post hospital discharge. Psychological well-being, assessed by a 6- domain psychological well-being instrument and a positive affect summary scale, will be used to examine patterns of association with functional status over the 5 time points outlined in aim 1. 3. Examine whether psychological well-being modifies ethnic health disparities associated with functional status during hospitalization and up to one-year post hospital discharge.
This aim will allow us to examine how ethnic group (non-Hispanic whites, non-Hispanic blacks and Hispanics) interacts with psychological well-being to influence functional status over the 5 time points outlined in aim 1. To explore our aims, we plan to follow up an ethnically diverse sample of 800 older patients (non-Hispanic whites, non-Hispanic blacks and Hispanics) admitted to the Acute Care for Elders (ACE) unit at the University of Texas Medical Branch. Older adults enrolled in the study will be assessed at five time points: within 24 hours of hospital admission, within 24 hours of hospital discharge and 1, 6 and 12 months post discharge. The five time points will allow us not only to examine overall patterns of effect between functional status and psychological well-being but it will also allow us to examine patterns of effect over distinct time periods including hospitalization and post discharge. The three post discharge follow up interviews will further allow us to examine and explain associations between functional status and psychological well-being in relation to short (1 month) and longer term (6 and 12 month) recovery patterns. A central goal of the current application is to examine whether psychological well-being can influence the risk for functional status decline associated with hospitalization in an ethnically diverse older patient population.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
7R01AG031178-07
Application #
8782529
Study Section
Social Psychology, Personality and Interpersonal Processes Study Section (SPIP)
Program Officer
Nielsen, Lisbeth
Project Start
2008-08-01
Project End
2014-06-30
Budget Start
2014-01-01
Budget End
2014-06-30
Support Year
Fiscal Year
2014
Total Cost
$282,051
Indirect Cost
$98,304
Name
University of Maryland Baltimore
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Ostir, Glenn V; Berges, Ivonne M; Kuo, Yong-Fang et al. (2013) Mobility activity and its value as a prognostic indicator of survival in hospitalized older adults. J Am Geriatr Soc 61:551-7
Fisher, Steve R; Graham, James E; Brown, Cynthia J et al. (2012) Factors that differentiate level of ambulation in hospitalised older adults. Age Ageing 41:107-11
AlGhatrif, Majd; Al Ghatrif, Majd; Kuo, Yong-Fang et al. (2011) Trends in hypertension prevalence, awareness, treatment and control in older Mexican Americans, 1993-2005. Ann Epidemiol 21:15-25
Ostir, Glenn V; Berges, Ivonne-M; Ottenbacher, Allison et al. (2011) Patterns of change in depression after stroke. J Am Geriatr Soc 59:314-20
Fisher, Steve R; Galloway, Rebecca V; Kuo, Yong-Fang et al. (2011) Pilot study examining the association between ambulatory activity and falls among hospitalized older adults. Arch Phys Med Rehabil 92:2090-2
Berges, Ivonne-Marie; Seale, Gary; Ostir, Glenn V (2011) Positive affect and pain ratings in persons with stroke. Rehabil Psychol 56:52-7
Fisher, Steve R; Goodwin, James S; Protas, Elizabeth J et al. (2011) Ambulatory activity of older adults hospitalized with acute medical illness. J Am Geriatr Soc 59:91-5
Masel, Meredith C; Raji, Mukaila; Peek, M Kristen (2010) Education and physical activity mediate the relationship between ethnicity and cognitive function in late middle-aged adults. Ethn Health 15:283-302
Beard, Holly A; Markides, Kyriakos S; Al Ghatrif, Majd et al. (2010) Trends in diabetes medication use and prevalence of geriatric syndromes in older Mexican Americans from 1993/1994 to 2004/2005. Ann Pharmacother 44:1376-83
Raji, Mukaila A; Al Snih, Soham; Ostir, Glenn V et al. (2010) Cognitive status and future risk of frailty in older Mexican Americans. J Gerontol A Biol Sci Med Sci 65:1228-34

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