Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029646-07
Application #
2065120
Study Section
Special Emphasis Panel (ZRG5-MBC-2 (03))
Project Start
1990-03-01
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Harvard University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Hartley, Mary-Anne; Eren, Remzi O; Rossi, Matteo et al. (2018) Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1?. Microb Cell 5:137-149
Robinson, John I; Beverley, Stephen M (2018) Concentration of 2'C-methyladenosine triphosphate by Leishmania guyanensis enables specific inhibition of Leishmania RNA virus 1 via its RNA polymerase. J Biol Chem 293:6460-6469
Brettmann, Erin A; Lye, Lon-Fye; Beverley, Stephen M (2018) Spontaneous excision and facilitated recovery as a control for phenotypes arising from RNA interference and other dominant transgenes. Mol Biochem Parasitol 220:42-45
Eren, Remzi Onur; Kopelyanskiy, Dmitry; Moreau, Dimitri et al. (2018) Development of a semi-automated image-based high-throughput drug screening system. Front Biosci (Elite Ed) 10:242-253
Davenport, Bennett J; Martin, Casey G; Beverley, Stephen M et al. (2018) SODB1 is essential for Leishmania major infection of macrophages and pathogenesis in mice. PLoS Negl Trop Dis 12:e0006921
Grybchuk, Danyil; Akopyants, Natalia S; Kostygov, Alexei Y et al. (2018) Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. Proc Natl Acad Sci U S A 115:E506-E515
Kohl, Kid; Zangger, Haroun; Rossi, Matteo et al. (2018) Importance of polyphosphate in the Leishmania life cycle. Microb Cell 5:371-384
Iantorno, Stefano A; Durrant, Caroline; Khan, Asis et al. (2017) Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage. MBio 8:
Kuhlmann, F Matthew; Robinson, John I; Bluemling, Gregory R et al. (2017) Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor. Proc Natl Acad Sci U S A 114:E811-E819
Castiglioni, Patrik; Hartley, Mary-Anne; Rossi, Matteo et al. (2017) Exacerbated Leishmaniasis Caused by a Viral Endosymbiont can be Prevented by Immunization with Its Viral Capsid. PLoS Negl Trop Dis 11:e0005240

Showing the most recent 10 out of 104 publications