Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037312-03
Application #
2074013
Study Section
Special Emphasis Panel (SRC (75))
Project Start
1994-09-30
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Crother, Timothy R; Champion, Cheryl I; Whitelegge, Julian P et al. (2004) Temporal analysis of the antigenic composition of Borrelia burgdorferi during infection in rabbit skin. Infect Immun 72:5063-72
Crother, Timothy R; Champion, Cheryl I; Wu, Xiao-Yang et al. (2003) Antigenic composition of Borrelia burgdorferi during infection of SCID mice. Infect Immun 71:3419-28
Shang, E S; Wu, X Y; Lovett, M A et al. (2001) Homologous and heterologous Borrelia burgdorferi challenge of infection-derived immune rabbits using host-adapted organisms. Infect Immun 69:593-8
Chong-Cerrillo, C; Shang, E S; Blanco, D R et al. (2001) Immunohistochemical analysis of Lyme disease in the skin of naive and infection-immune rabbits following challenge. Infect Immun 69:4094-102
Exner, M M; Wu, X; Blanco, D R et al. (2000) Protection elicited by native outer membrane protein Oms66 (p66) against host-adapted Borrelia burgdorferi: conformational nature of bactericidal epitopes. Infect Immun 68:2647-54
Shang, E S; Champion, C I; Wu, X Y et al. (2000) Comparison of protection in rabbits against host-adapted and cultivated Borrelia burgdorferi following infection-derived immunity or immunization with outer membrane vesicles or outer surface protein A. Infect Immun 68:4189-99
Blanco, D R; Whitelegge, J P; Miller, J N et al. (1999) Demonstration by mass spectrometry that purified native Treponema pallidum rare outer membrane protein 1 (Tromp1) has a cleaved signal peptide. J Bacteriol 181:5094-8
Zhang, H H; Blanco, D R; Exner, M M et al. (1999) Renaturation of recombinant Treponema pallidum rare outer membrane protein 1 into a trimeric, hydrophobic, and porin-active conformation. J Bacteriol 181:7168-75
Blanco, D R; Champion, C I; Lewinski, M A et al. (1999) Immunization with Treponema pallidum outer membrane vesicles induces high-titer complement-dependent treponemicidal activity and aggregation of T. pallidum rare outer membrane proteins (TROMPs). J Immunol 163:2741-6
Shang, E S; Skare, J T; Exner, M M et al. (1998) Isolation and characterization of the outer membrane of Borrelia hermsii. Infect Immun 66:1082-91

Showing the most recent 10 out of 17 publications