Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI049453-02
Application #
6831309
Study Section
Immunobiology Study Section (IMB)
Program Officer
Nabavi, Nasrin N
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$370,000
Indirect Cost
Name
La Jolla Institute
Department
Type
DUNS #
603880287
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Duan, Wei; Croft, Michael (2014) Control of regulatory T cells and airway tolerance by lung macrophages and dendritic cells. Ann Am Thorac Soc 11 Suppl 5:S306-13
Croft, Michael (2014) The TNF family in T cell differentiation and function--unanswered questions and future directions. Semin Immunol 26:183-90
Nagashima, Hiroyuki; Okuyama, Yuko; Asao, Atsuko et al. (2014) The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat Immunol 15:449-56
Boettler, Tobias; Choi, Youn Soo; Salek-Ardakani, Shahram et al. (2013) Exogenous OX40 stimulation during lymphocytic choriomeningitis virus infection impairs follicular Th cell differentiation and diverts CD4 T cells into the effector lineage by upregulating Blimp-1. J Immunol 191:5026-35
Croft, Michael; Benedict, Chris A; Ware, Carl F (2013) Clinical targeting of the TNF and TNFR superfamilies. Nat Rev Drug Discov 12:147-68
Boettler, Tobias; Moeckel, Friedrich; Cheng, Yang et al. (2012) OX40 facilitates control of a persistent virus infection. PLoS Pathog 8:e1002913
Croft, Michael; Duan, Wei; Choi, Heonsik et al. (2012) TNF superfamily in inflammatory disease: translating basic insights. Trends Immunol 33:144-52
Soroosh, Pejman; Doherty, Taylor A; So, Takanori et al. (2011) Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations. J Exp Med 208:797-809
So, Takanori; Choi, Heonsik; Croft, Michael (2011) OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signaling. J Immunol 186:3547-55
Doherty, Taylor A; Croft, Michael (2011) Therapeutic potential of targeting TNF/TNFR family members in asthma. Immunotherapy 3:919-21

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