Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI050128-02
Application #
6686415
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Duncan, Rory A
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$308,000
Indirect Cost

  Institution

Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Gontijo, Fabiano de Assis; de Melo, Amanda Teixeira; Pascon, Renata C et al. (2017) The role of Aspartyl aminopeptidase (Ape4) in Cryptococcus neoformans virulence and authophagy. PLoS One 12:e0177461
Esher, Shannon K; Ost, Kyla S; Kozubowski, Lukasz et al. (2016) Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis. mSphere 1:
Nichols, Connie B; Ost, Kyla S; Grogan, Dayton P et al. (2015) Impact of Protein Palmitoylation on the Virulence Potential of Cryptococcus neoformans. Eukaryot Cell 14:626-35
O'Meara, Teresa R; Xu, Wenjie; Selvig, Kyla M et al. (2014) The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host. Mol Cell Biol 34:673-84
de Gontijo, Fabiano Assis; Pascon, Renata C; Fernandes, Larissa et al. (2014) The role of the de novo pyrimidine biosynthetic pathway in Cryptococcus neoformans high temperature growth and virulence. Fungal Genet Biol 70:12-23
Selvig, Kyla; Ballou, Elizabeth R; Nichols, Connie B et al. (2013) Restricted substrate specificity for the geranylgeranyltransferase-I enzyme in Cryptococcus neoformans: implications for virulence. Eukaryot Cell 12:1462-71
Ballou, Elizabeth Ripley; Selvig, Kyla; Narloch, Jessica L et al. (2013) Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans. Fungal Genet Biol 57:58-75
O'Meara, Teresa R; Holmer, Stephanie M; Selvig, Kyla et al. (2013) Cryptococcus neoformans Rim101 is associated with cell wall remodeling and evasion of the host immune responses. MBio 4:
Ballou, Elizabeth Ripley; Kozubowski, Lukasz; Nichols, Connie B et al. (2013) Ras1 acts through duplicated Cdc42 and Rac proteins to regulate morphogenesis and pathogenesis in the human fungal pathogen Cryptococcus neoformans. PLoS Genet 9:e1003687
Shen, Gui; Zhou, Erxun; Alspaugh, J Andrew et al. (2012) Wsp1 is downstream of Cin1 and regulates vesicle transport and actin cytoskeleton as an effector of Cdc42 and Rac1 in Cryptococcus neoformans. Eukaryot Cell 11:471-81

Showing the most recent 10 out of 18 publications