targets for the treatment of cardiovascular disease and our current studies are likely to provide additional targets for the treatment of this important human parasitic disease. Project Description Page 6

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI076248-05
Application #
8197254
Study Section
Pathogenic Eukaryotes Study Section (PTHE)
Program Officer
Mcgugan, Glen C
Project Start
2007-12-15
Project End
2013-11-30
Budget Start
2011-12-01
Budget End
2013-11-30
Support Year
5
Fiscal Year
2012
Total Cost
$474,519
Indirect Cost
$188,664
Name
Albert Einstein College of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Freeman, Brandi D; Martins, Yuri C; Akide-Ndunge, Oscar B et al. (2016) Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria. PLoS Pathog 12:e1005477
Martins, Yuri C; Freeman, Brandi D; Akide Ndunge, Oscar B et al. (2016) Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65. Am J Pathol 186:2957-2969
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Nagajyothi, Fnu; Kuliawat, Regina; Kusminski, Christine M et al. (2013) Alterations in glucose homeostasis in a murine model of Chagas disease. Am J Pathol 182:886-94
Mukherjee, Shankar; Sadekar, Nikaeta; Ashton, Anthony W et al. (2013) Identification of a functional prostanoid-like receptor in the protozoan parasite, Trypanosoma cruzi. Parasitol Res 112:1417-25
Jelicks, Linda A; Lisanti, Michael P; Machado, Fabiana S et al. (2013) Imaging of small-animal models of infectious diseases. Am J Pathol 182:296-304

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