Abstract

targets for the treatment of cardiovascular disease and our current studies are likely to provide additional targets for the treatment of this important human parasitic disease. Project Description Page 6

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI076248-05
Application #
8197254
Study Section
Pathogenic Eukaryotes Study Section (PTHE)
Program Officer
Mcgugan, Glen C
Project Start
2007-12-15
Project End
2013-11-30
Budget Start
2011-12-01
Budget End
2013-11-30
Support Year
5
Fiscal Year
2012
Total Cost
$474,519
Indirect Cost
$188,664

  Institution

Name
Albert Einstein College of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461

  Publications

D'Orléans-Juste, Pedro; Akide Ndunge, Oscar B; Desbiens, Louisane et al. (2018) Endothelins in inflammatory neurological diseases. Pharmacol Ther :
Freeman, Brandi D; Martins, Yuri C; Akide-Ndunge, Oscar B et al. (2016) Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria. PLoS Pathog 12:e1005477
Martins, Yuri C; Freeman, Brandi D; Akide Ndunge, Oscar B et al. (2016) Endothelin-1 Treatment Induces an Experimental Cerebral Malaria-Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65. Am J Pathol 186:2957-2969
Mukherjee, Shankar; Mukhopadhyay, Aparna; Andriani, Grasiella et al. (2015) Trypanosoma cruzi invasion is associated with trogocytosis. Microbes Infect 17:62-70
Brant, Fatima; Miranda, Aline S; Esper, Lisia et al. (2014) Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection. Infect Immun 82:3127-40
Freeman, Brandi D; Machado, Fabiana S; Tanowitz, Herbert B et al. (2014) Endothelin-1 and its role in the pathogenesis of infectious diseases. Life Sci 118:110-9
Burke, Shoshana; Nagajyothi, Fnu; Thi, Mia M et al. (2014) Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease. Microbes Infect 16:893-901
Malvestio, Lygia M; Celes, Mara R N; Milanezi, Cristiane et al. (2014) Role of dystrophin in acute Trypanosoma cruzi infection. Microbes Infect 16:768-77
Nagajyothi, Fnu; Kuliawat, Regina; Kusminski, Christine M et al. (2013) Alterations in glucose homeostasis in a murine model of Chagas disease. Am J Pathol 182:886-94
Jelicks, Linda A; Lisanti, Michael P; Machado, Fabiana S et al. (2013) Imaging of small-animal models of infectious diseases. Am J Pathol 182:296-304

Showing the most recent 10 out of 67 publications