Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
7R01AR041053-05
Application #
2080452
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1992-09-30
Project End
1997-08-31
Budget Start
1996-08-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Davis
Department
Biochemistry
Type
Schools of Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Tepper, C G; Seldin, M F (1999) Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma. Blood 94:1727-37
Chinnaiyan, A M; Tepper, C G; Seldin, M F et al. (1996) FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis. J Biol Chem 271:4961-5
Goel, N; Ulrich, D T; St Clair, E W et al. (1995) Lack of correlation between serum soluble Fas/APO-1 levels and autoimmune disease. Arthritis Rheum 38:1738-43
Yao, Z; Fanslow, W C; Seldin, M F et al. (1995) Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3:811-21
Tepper, C G; Jayadev, S; Liu, B et al. (1995) Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc Natl Acad Sci U S A 92:8443-7
Baum, P R; Gayle 3rd, R B; Ramsdell, F et al. (1994) Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34. EMBO J 13:3992-4001
Lynch, D H; Watson, M L; Alderson, M R et al. (1994) The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity 1:131-6
Weinberg, J B; Granger, D L; Pisetsky, D S et al. (1994) The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally admi J Exp Med 179:651-60
Watson, M L; Rao, J K; Gilkeson, G S et al. (1992) Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med 176:1645-56