Femoroacetabular impingement (FAI) is a common mechanism leading to hip injury, leading to hip pain and early osteoarthritis (OA). While a benefit to FAI surgery has been suggested, no studies have identified prognostic factors associated with successful FAI arthroscopy, leaving surgeons without adequate indications. Despite this lack of evidence, rapid increase in the use of hip arthroscopy is reminiscent of that seen for knee and shoulder arthroscopy. The enthusiasm for hip arthroscopy has clearly grown at a faster rate than our ability to accumulate information. The patient population currently treated operatively for FAI is highly heterogeneous, making a randomized controlled trial (RCT) extremely difficult to mount. This observational study will establish clinical equipoise for a futue RCT.
Aims /Methods:
(Aim 1) : Determine the clinical and morphologic factors associated with successful FAI management. """"""""Success"""""""" will be defined by an improvement in pain and function measured using a hip-specific patient-reported outcome instrument 2 years post-presentation. Operative and non-operative patients will be propensity score matched to limit the study to those eligible for either therapeutic approach. Patient characteristics and bony morphology will be assessed with regard to the development of hip pain and early chondro-labral pathology and their effect on patient outcome at 2 years.
(Aim 2). Measure the effect of FAI arthroscopy on subsequent cartilage degeneration. A random sample of patients who had initial quantitative MRI assessment (T2 mapping and T1 rho) will be followed up with MRI 5 years after surgery to assess cartilage deterioration. Accomplishing these aims will allow us to test 3 hypotheses: Hypothesis 1A. Patients undergoing FAI arthroscopy for certain indications (e.g., cam lesion) will have improved function at 2 years compared to patients who choose non-operative management. Hypothesis 1B. Arthroscopic correction of abnormal bony morphology associated with intra-articular derangement will result in improved patient outcomes compared to surgical interventions that do not address bony morphology. Hypothesis 2. Progression of cartilage degeneration will be less pronounced among patients undergoing FAI arthroscopy for bony morphology correction than those treated non-operatively for similar morphology. Benefits:
The first aim will clarify prognostic factors associated with improved outcomes and will provide surgeons with evidence for appropriate indications for FAI treatment while the second aim will provide the first evidence that appropriately identified patients have a decreased risk of early OA. Achieving these aims, we will identify appropriate indications, prognostic factors, and treatment algorithms for FAI. We will also have identified a more homogeneous subset of patients for which an RCT will determine the best course of treatment. The use of propensity score matching in the setting of arthroscopic surgery will also aid other researchers struggling with the issues of generalizability and timely completion of RCTs.

Public Health Relevance

Femoroacetabular impingement (FAI) is a difficult form of hip pathology believed to lead to hip osteoarthritis that until recent has lacked a safe and potentiall effective surgical intervention. However, the indications, prognostic factors, and long term outcomes of hip arthroscopy compared to conservative therapy for FAI remain unknown. This observational prospective cohort study proposes to use a propensity score matching approach to assess the safety and effectiveness of FAI surgery compared to nonoperative management as well as identify the patients most likely to benefit from surgery as well as the longer term effect on cartilage degeneration.

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Research Project (R01)
Project #
Application #
Study Section
Skeletal Biology Structure and Regeneration Study Section (SBSR)
Program Officer
Panagis, James S
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Hospital for Special Surgery
New York
United States
Zip Code
Mehta, Nabil; Chamberlin, Peter; Marx, Robert G et al. (2018) Defining the Learning Curve for Hip Arthroscopy: A Threshold Analysis of the Volume-Outcomes Relationship. Am J Sports Med 46:1284-1293
Degen, Ryan M; Pan, Ting J; Chang, Brenda et al. (2017) Risk of failure of primary hip arthroscopy-a population-based study. J Hip Preserv Surg 4:214-223
Degen, Ryan M; Bernard, Johnathan A; Pan, Ting J et al. (2017) Hip arthroscopy utilization and associated complications: a population-based analysis. J Hip Preserv Surg 4:240-249
Mehta, Nabil; Steiner, Claire; Fields, Kara G et al. (2017) Using Mobile Tracking Technology to Visualize the Trajectory of Recovery After Hip Arthroscopy: a Case Report. HSS J 13:194-200