Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA015523-22
Application #
2086356
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1977-05-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Balagurumoorthy, Pichumani; Xu, Xiang; Wang, Ketai et al. (2012) Effect of distance between decaying (125)I and DNA on Auger-electron induced double-strand break yield. Int J Radiat Biol 88:998-1008
Mamlouk, Omar; Balagurumoorthy, Pichumani; Wang, Ketai et al. (2012) Bystander effect in tumor cells produced by Iodine-125 labeled human lymphocytes. Int J Radiat Biol 88:1019-27
Kassis, Amin I (2011) Molecular and cellular radiobiological effects of Auger emitting radionuclides. Radiat Prot Dosimetry 143:241-7
Balagurumoorthy, Pichumani; Adelstein, S James; Kassis, Amin I (2011) Novel method for quantifying radiation-induced single-strand-break yields in plasmid DNA highlights 10-fold discrepancy. Anal Biochem 417:242-6
Zhu, Xuping; Palmer, Matthew R; Makrigiorgos, G Mike et al. (2010) Solid-tumor radionuclide therapy dosimetry: new paradigms in view of tumor microenvironment and angiogenesis. Med Phys 37:2974-84
Singh, Amarjit; Yang, Yongliang; Adelstein, S James et al. (2008) Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution. Int J Radiat Biol 84:1001-10
Balagurumoorthy, Pichumani; Adelstein, S James; Kassis, Amin I (2008) Method to eliminate linear DNA from mixture containing nicked circular, supercoiled, and linear plasmid DNA. Anal Biochem 381:172-4
Balagurumoorthy, Pichumani; Chen, Kai; Adelstein, S James et al. (2008) Auger electron-induced double-strand breaks depend on DNA topology. Radiat Res 170:70-82
Kassis, Amin I (2008) Therapeutic radionuclides: biophysical and radiobiologic principles. Semin Nucl Med 38:358-66
Balagurumoorthy, Pichumani; Wang, Ketai; Adelstein, S James et al. (2008) DNA double-strand breaks induced by decay of (123)I-labeled Hoechst 33342: role of DNA topology. Int J Radiat Biol 84:976-83

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