Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA019033-20
Application #
2086742
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1976-06-30
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Nguyen, Minh H; Imanishi, Masashi; Kurogi, Taichi et al. (2018) Synthetic Access to the Mandelalide Family of Macrolides: Development of an Anion Relay Chemistry Strategy. J Org Chem 83:4287-4306
Ai, Yanran; Kozytska, Mariya V; Zou, Yike et al. (2018) Total Synthesis of the Marine Phosphomacrolide, (-)-Enigmazole A, Exploiting Multicomponent Type I Anion Relay Chemistry (ARC) in Conjunction with a Late-Stage Petasis-Ferrier Union/Rearrangement. J Org Chem 83:6110-6126
Zou, Yike; Li, Xiangqin; Yang, Yun et al. (2018) Total Synthesis of (-)-Nodulisporic Acids D, C, and B: Evolution of a Unified Synthetic Strategy. J Am Chem Soc 140:9502-9511
Deng, Yifan; Liu, Qi; Smith 3rd, Amos B (2017) Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations. J Am Chem Soc 139:9487-9490
Montgomery, Thomas D; Smith 3rd, Amos B (2017) ?-Silyl Amides: Effective Bifunctional Lynchpins for Type I Anion Relay Chemistry. Org Lett 19:6216-6219
Liu, Qi; Deng, Yifan; Smith 3rd, Amos B (2017) Total Synthesis of (-)-Nahuoic Acid Ci (Bii). J Am Chem Soc 139:13668-13671
Liu, Qi; Chen, Yu; Zhang, Xiao et al. (2017) Type II Anion Relay Chemistry: Conformational Constraints To Achieve Effective [1,5]-Vinyl Brook Rearrangements. J Am Chem Soc 139:8710-8717
Nazari, Mohamad; Serrill, Jeffrey D; Wan, Xuemei et al. (2017) New Mandelalides Expand a Macrolide Series of Mitochondrial Inhibitors. J Med Chem 60:7850-7862
Adams, Gregory L; Smith 3rd, Amos B (2016) The Chemistry of the Akuammiline Alkaloids. Alkaloids Chem Biol 76:171-257
Liu, Qi; An, Chihui; TenDyke, Karen et al. (2016) Design, Synthesis, and Evaluation of Irciniastatin Analogues: Simplification of the Tetrahydropyran Core and the C(11) Substituents. J Org Chem 81:1930-42

Showing the most recent 10 out of 61 publications