Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA041556-10
Application #
2090489
Study Section
Pathology B Study Section (PTHB)
Project Start
1986-07-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Xie, Wen; Aisner, Seena; Baredes, Soly et al. (2013) Alterations of Smad expression and activation in defining 2 subtypes of human head and neck squamous cell carcinoma. Head Neck 35:76-85
Cohen-Solal, Karine A; Merrigan, Kim T; Chan, Joseph L-K et al. (2011) Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-?-mediated growth inhibition. Pigment Cell Melanoma Res 24:512-24
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Xie, Wen; Bharathy, Savita; Kim, David et al. (2003) Frequent alterations of Smad signaling in human head and neck squamous cell carcinomas: a tissue microarray analysis. Oncol Res 14:61-73
Liu, Chenghai; Gaca, Marianna D A; Swenson, E Scott et al. (2003) Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent. J Biol Chem 278:11721-8
Xie, Wen; Mertens, Joachim C; Reiss, Daniel J et al. (2002) Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study. Cancer Res 62:497-505

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