Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA095039-02
Application #
6690739
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Poland, Alan P
Project Start
2002-12-01
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$200,094
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Seiler, Christopher L; Fernandez, Jenna; Koerperich, Zoe et al. (2018) Maintenance DNA Methyltransferase Activity in the Presence of Oxidized Forms of 5-Methylcytosine: Structural Basis for Ten Eleven Translocation-Mediated DNA Demethylation. Biochemistry 57:6061-6069
Kotandeniya, D; Seiler, C L; Fernandez, J et al. (2018) Can 5-methylcytosine analogues with extended alkyl side chains guide DNA methylation? Chem Commun (Camb) 54:1061-1064
Ji, Shaofei; Shao, Hongzhao; Han, Qiyuan et al. (2017) Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks. Angew Chem Int Ed Engl 56:14130-14134
Pujari, Suresh S; Tretyakova, Natalia (2017) Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts. Chem Res Toxicol 30:434-452
Wickramaratne, Susith; Seiler, Christopher L; Tretyakova, Natalia Y (2015) Synthesis of DNA Oligodeoxynucleotides Containing Site-Specific 1,3-Butadiene-Deoxyadenosine Lesions. Curr Protoc Nucleic Acid Chem 61:4.61.1-22
Ming, Xun; Matter, Brock; Song, Matthew et al. (2014) Mapping structurally defined guanine oxidation products along DNA duplexes: influence of local sequence context and endogenous cytosine methylation. J Am Chem Soc 136:4223-35
Kotandeniya, Delshanee; Murphy, Daniel; Yan, Shuo et al. (2013) Kinetics of O(6)-pyridyloxobutyl-2'-deoxyguanosine repair by human O(6)-alkylguanine DNA alkyltransferase. Biochemistry 52:4075-88
Tretyakova, Natalia; Villalta, Peter W; Kotapati, Srikanth (2013) Mass spectrometry of structurally modified DNA. Chem Rev 113:2395-436
Kim, Min Young; Lim, Chang Hoon; Trudel, Laura J et al. (2012) Delivery method, target gene structure, and growth properties of target cells impact mutagenic responses to reactive nitrogen and oxygen species. Chem Res Toxicol 25:873-83
Tretyakova, Natalia; Goggin, Melissa; Sangaraju, Dewakar et al. (2012) Quantitation of DNA adducts by stable isotope dilution mass spectrometry. Chem Res Toxicol 25:2007-35

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