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Queener, S F; Cody, V; Pace, J et al. (2013) Trimethoprim resistance of dihydrofolate reductase variants from clinical isolates of Pneumocystis jirovecii. Antimicrob Agents Chemother 57:4990-8
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Cody, Vivian; Pace, Jim; Queener, Sherry F et al. (2013) Kinetic and structural analysis for potent antifolate inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and human dihydrofolate reductases and their active-site variants. Antimicrob Agents Chemother 57:2669-77
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Gangjee, Aleem; Namjoshi, Ojas A; Yu, Jianming et al. (2013) N2-Trimethylacetyl substituted and unsubstituted-N4-phenylsubstituted-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines: design, cellular receptor tyrosine kinase inhibitory activities and in vivo evaluation as antiangiogenic, antimetastati Bioorg Med Chem 21:1312-23
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Gangjee, Aleem; Zaware, Nilesh; Raghavan, Sudhir et al. (2013) Synthesis and biological activity of 5-chloro-N?-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic agents. Bioorg Med Chem 21:1857-64
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Gangjee, Aleem; Zhao, Ying; Ihnat, Michael A et al. (2012) Novel tricyclic indeno[2,1-d]pyrimidines with dual antiangiogenic and cytotoxic activities as potent antitumor agents. Bioorg Med Chem 20:4217-25
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Gangjee, Aleem; Zaware, Nilesh; Raghavan, Sudhir et al. (2012) Nýýý-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation. Bioorg Med Chem 20:2444-54
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Gangjee, Aleem; Kurup, Sonali; Ihnat, Michael A et al. (2012) N?-Aryl-6-substitutedphenylmethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as receptor tyrosine kinase inhibitors. Bioorg Med Chem 20:910-4
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Gangjee, Aleem; Namjoshi, Ojas A; Keller, Staci N et al. (2011) 2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance. Bioorg Med Chem 19:4355-65
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Gangjee, Aleem; Kurup, Sonali; Ihnat, Michael A et al. (2010) Synthesis and biological activity of N(4)-phenylsubstituted-6-(2,4-dichloro phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic and antitumor agents. Bioorg Med Chem 18:3575-87
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Gangjee, Aleem; Zhao, Ying; Lin, Lu et al. (2010) Synthesis and discovery of water-soluble microtubule targeting agents that bind to the colchicine site on tubulin and circumvent Pgp mediated resistance. J Med Chem 53:8116-28
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Showing the most recent 10 out of 19 publications
