African Americans have the highest incidence and mortality and are less likely than whites to have screening for colorectal cancer (CRC). We recently completed a five-year randomized controlled community intervention trial that demonstrated the efficacy of a small group education intervention (now named EPICS or Educational Program to Increase Colorectal Cancer Screening) that doubled the CRC screening rate compared to the control group rate. EPICS was then put into practice in partnership with the local health department and was equally effective. We are now disseminating the intervention across the state of Georgia. In this application we propose a national dissemination and implementation study. We propose using Rogers'Diffusion of Innovation Theory and Glasgow's RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) evaluation framework to pursue the following specific aims: 1) test passive and active approaches to disseminating EPICS to increase screening rates for colorectal cancer among African Americans;2) measure the extent to which EPICS is accepted by community coalitions and the fidelity of implementation in various settings and 3) estimate the potential translatability and public health impact of EPICS. Diffusion of Innovations Theory will guide the process of EPICS dissemination and RE-AIM will be used to assess this dissemination and its impact. For this study we propose a cluster randomized controlled trial of 20 community coalitions from across the United States, assigned to one of four conditions: (1, passive) web-based access to facilitator training materials and toolkits without technical assistance (TA);(2, passive) the sam as 1, but with TA;(3, active) in-person access (IP) to facilitator training materials and toolkits without TA and (4, active) IP access to facilitator training materials and toolkits with TA. Each community coalition will partner with three settings for implementation: a church, clinic and community site. African Americans, 50-74 years of age, who are not current on CRC screening are eligible for study participation (n=7,200 or n=360 eligible individuals per community coalition). This assumes a sample size of 1800 per study arm, a significance level of 5% (i.e. alpha = 0.05), and a two-sided two-group chi-square test of proportions. Assuming that we observe in our study an increase in screening rates of colorectal cancer among participants in active arms compared to screening rates among participants in the passive arms, we will have greater than 99% power to detect statistically significant differences in the proportions. All statistical tests proposed for this study will be two-sided and will be performed using a significance level of 5% (i.e., alpha=0.05).
Colorectal Cancer (CRC) is one of the most important causes of cancer deaths (second to lung cancer), with persistent disparities documented by race/ethnicity. This project seeks to demonstrate the effectiveness of an intervention proven efficacious among African Americans, and to document its utility by describing its transition from research to real world settings. Successfully implementing the core elements of the intervention will increase CRC screening among African Americans and will help reduce CRC incidence and mortality.
|Coughlin, Steven S; Smith, Selina A (2016) A review of community-based participatory research studies to promote physical activity among African Americans. J Ga Public Health Assoc 5:220-227|
|Webb, Nancy C; Smith, Selina A (2016) How can we promote mentored student research in Georgia? J Ga Public Health Assoc 6:180-183|
|Smith, Selina A; Claridy, Mechelle D; Whitehead, Mary S et al. (2016) Factors associated with body mass index among African American breast cancer survivors. J Ga Public Health Assoc 5:259-265|
|Holliday, Rhonda Conerly; Braithwaite, Ronald L; Yancey, Elleen et al. (2016) Substance Use Correlates of Depression among African American Male Inmates. J Health Care Poor Underserved 27:181-93|
|Smith, Selina Ann; Whitehead, Mary Smith; Sheats, Joyce et al. (2016) A Community-Engaged Approach to Developing a Mobile Cancer Prevention App: The mCPA Study Protocol. JMIR Res Protoc 5:e34|
|Yoo, Wonsuk; De, Subhendu; Wilkins, Thad et al. (2016) Age, Race and Regional Disparities in Colorectal Cancer Incidence Rates in Georgia between 2000 and 2012. Ann Public Health Res 3:|
|Stephens, Torrance; Holliday, Rhonda Conerly; Hopkins, Shakita et al. (2016) Correlates of African American female adolescent offenders 3, 4-Methylenedioxymethamphetamine (MDMA or "Ecstasy") use and sexually transmitted infection morbidity. J Hum Behav Soc Environ 26:194-201|
|Ansa, Benjamin E; White, Sashia; Chung, Yunmi et al. (2016) Trends in HIV Testing among Adults in Georgia: Analysis of the 2011-2015 BRFSS Data. Int J Environ Res Public Health 13:|
|Smith, Selina A; Braithwaite, Ronald L (2016) Introduction to Public Health and Incarceration: Social Justice Matters. J Health Care Poor Underserved 27:1-4|
|Smith, Selina A; Whitehead, Mary S; Sheats, Joyce Q et al. (2016) Formative research to develop a lifestyle application (app) for African American breast cancer survivors. J Ga Public Health Assoc 6:50-59|
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