Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA002194-16A1S1
Application #
2116520
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1985-02-01
Project End
1998-01-31
Budget Start
1995-07-01
Budget End
1996-01-31
Support Year
16
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Toledo
Department
Physiology
Type
Schools of Medicine
DUNS #
807418939
City
Toledo
State
OH
Country
United States
Zip Code
43614
Dong, Yu; Rosenberg, Howard C (2004) Brief seizure activity alters Ca2+/calmodulin dependent protein kinase II dephosphorylation and subcellular distribution in rat brain for several hours. Neurosci Lett 357:95-8
Dong, Yu; Rosenberg, Howard C (2004) Prolonged changes in Ca2+/calmodulin-dependent protein kinase II after a brief pentylenetetrazol seizure; potential role in kindling. Epilepsy Res 58:107-17
Li, M; Szabo, A; Rosenberg, H C (2001) Evaluation of native GABA(A) receptors containing an alpha 5 subunit. Eur J Pharmacol 413:63-72
Li, M; Szabo, A; Rosenberg, H C (2000) Down-regulation of benzodiazepine binding to alpha 5 subunit-containing gamma-aminobutyric Acid(A) receptors in tolerant rat brain indicates particular involvement of the hippocampal CA1 region. J Pharmacol Exp Ther 295:689-96
Walsh, L A; Li, M; Zhao, T J et al. (1999) Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with No effect on benzodiazepine binding site density. J Pharmacol Exp Ther 289:1626-33
Zhao, T J; Li, M; Chiu, T H et al. (1998) Decreased benzodiazepine binding with little effect on gamma-aminobutyric acid binding in rat brain after treatment with antisense oligodeoxynucleotide to the gamma-aminobutyric acidA receptor gamma-2 subunit. J Pharmacol Exp Ther 287:752-9
Zhao, T J; Rosenberg, H C; Chiu, T H (1996) Treatment with an antisense oligodeoxynucleotide to the GABAA receptor gamma 2 subunit increases convulsive threshold for beta-CCM, a benzodiazepine ""inverse agonist', in rats. Eur J Pharmacol 306:61-6
Tersigni, T J; Rosenberg, H C (1996) Local pressure application of cannabinoid agonists increases spontaneous activity of rat substantia nigra pars reticulata neurons without affecting response to iontophoretically-applied GABA. Brain Res 733:184-92
Rosenberg, H C (1995) Differential expression of benzodiazepine anticonvulsant cross-tolerance according to time following flurazepam or diazepam treatment. Pharmacol Biochem Behav 51:363-8
Wu, Y; Rosenberg, H C; Chiu, T H (1995) Rapid down-regulation of [3H]zolpidem binding to rat brain benzodiazepine receptors during flurazepam treatment. Eur J Pharmacol 278:125-32

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