Developmental-ecological theory posits that the initiation of substance use (SU) in childhood and adolescence is a function of reciprocal and interacting influences between individuals and their socio- environmental context. Yet, very little research has integrated risk and protective factors from multiple levels. Theoretically grounded research that delineates unique and interactive individual and contextual influences on early emerging SU is needed to guide the development of preventive interventions. We propose to test mediational and moderational relations among cognitive, peer, parental, community, and psychobiological/motivational factors as pathways to adolescent SU. Research in neuroscience suggests that changes in appetitive motivation during adolescence increases vulnerability to risky contexts. The proposed research will examine how shifts in appetitive motivation converge with community, parental, and peer contexts to influence both implicit and explicit beliefs supportive of SU and SU. A sample of 400 10-12 year old children assessed across 3-waves will allow for the examination of how changes in these constructs presage SU. Child motivational profiles based on approach, inhibition, and self-regulation will be assessed using laboratory tasks, physiological indicators, and parent reports. Multiple methods will be used to assess beliefs about SU, and peer, parental, and community context. A combination of latent profile, transition, multilevel, and growth analysis, will be used to examine: 1) trajectories of SU beliefs; 2) the direct, indirect, and reciprocal effects of context on SU beliefs and SU; and 3) the moderating effect of motivational profiles on the relation between context and beliefs and SU. This study examines developmental changes in beliefs related to adolescent SU, and modulation of contextual influences by psychobiological motivational profiles. The proposed research has the potential to provide important direction for how the content of SU preventive interventions could be tailored for specific populations and to target relevant etiological processes for maximal effectiveness. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA020171-03
Application #
7413610
Study Section
Special Emphasis Panel (ZRG1-RPHB-H (90))
Program Officer
Price, Leshawndra N
Project Start
2006-08-01
Project End
2011-04-30
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
3
Fiscal Year
2008
Total Cost
$563,541
Indirect Cost
Name
State University of New York at Buffalo
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Colder, Craig R; Shyhalla, Kathleen; Frndak, Seth E (2018) Early alcohol use with parental permission: Psychosocial characteristics and drinking in late adolescence. Addict Behav 76:82-87
Meisel, Samuel N; Read, Jennifer P; Mullin, Sarah et al. (2018) Changes in implicit alcohol attitudes across adolescence, and associations with emerging alcohol use: Testing the reciprocal determinism hypothesis. Psychol Addict Behav 32:738-748
Scalco, Matthew D; Colder, Craig R (2017) Trajectories of marijuana use from late childhood to late adolescence: Can Temperament × Experience interactions discriminate different trajectories of marijuana use? Dev Psychopathol 29:775-790
Colder, Craig R; Read, Jennifer P; Wieczorek, William F et al. (2017) Cognitive appraisals of alcohol use in early adolescence: Psychosocial predictors and reciprocal associations with alcohol use. J Early Adolesc 37:525-558
Scalco, Matthew D; Meisel, Samuel N; Colder, Craig R (2016) Misperception and accurate perception of close friend substance use in early adolescence: Developmental and intervention implications. Psychol Addict Behav 30:300-11
O'Connor, Roisin M; Colder, Craig R (2015) The Prospective Joint Effects of Self-Regulation and Impulsive Processes on Early Adolescence Alcohol Use. J Stud Alcohol Drugs 76:884-94
Scalco, Matthew D; Trucco, Elisa M; Coffman, Donna L et al. (2015) Selection and Socialization Effects in Early Adolescent Alcohol Use: A Propensity Score Analysis. J Abnorm Child Psychol 43:1131-43
Colder, Craig R; O'Connor, Roisin M; Read, Jennifer P et al. (2014) Growth trajectories of alcohol information processing and associations with escalation of drinking in early adolescence. Psychol Addict Behav 28:659-70
Scalco, Matthew D; Colder, Craig R; Hawk, Larry W et al. (2014) Internalizing and externalizing problem behavior and early adolescent substance use: a test of a latent variable interaction and conditional indirect effects. Psychol Addict Behav 28:828-40
Zehe, Jennifer M; Colder, Craig R (2014) A latent growth curve analysis of alcohol-use specific parenting and adolescent alcohol use. Addict Behav 39:1701-5

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