Smoking remains one of the biggest causes of premature morbidity and mortality. Nicotine addiction continues to challenge researchers to optimize their best interventions, and these challenges increase with efforts to integrate smoking cessation into multiple behavior change research and dissemination. Tailored intervention strategies have demonstrated effectiveness, yet much research remains to be done exploring optimal tailoring strategies. Transtheoretical model (TTM) tailored feedback on all 14 variables has been demonstrated to be a robust population cessation strategy across studies, producing 22-25% quit rates at 18-24 month final timepoints. This proposal seeks to find a subset of these variables that is optimal for tailoring, both minimizing response burden while maximizing effectiveness. Addiction variables have been demonstrated to predict smoking outcomes across studies as well, so we will integrate tailored feedback using TTM and addiction variables into an enhanced tailoring group. Enhanced addiction tailored feedback that both helps unmotivated smokers reduce their addiction and helps motivated smokers quit could lead to a breakthrough in population cessation. This proposal tests four types of TTM-tailoring for smoking cessation in an additive design: no treatment control group;Minimal tailoring (stage only);Moderate tailoring (stage, pros, cons, efficacy);Full TTM tailoring (all 14 TTM variables);and Enhanced TTM tailoring plus addiction variables. Smokers will be randomized to one of five treatment groups and evaluated at baseline, 6 months, 12 months, and 24 months. Treatment groups will receive tailored feedback at baseline, 6 months, and 12 months. Analyses will compare treatment groups on quit rates at the final timepoint to see how effectively each treatment helps smokers to quit. A series of mediation and moderation analyses will examine how each treatment works. This study has the potential to find an optimal tailoring strategy for population cessation that could accelerate future multiple behavior change research and dissemination efforts.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Project (R01)
Project #
Application #
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Denisco, Richard A
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Rhode Island
Internal Medicine/Medicine
Schools of Arts and Sciences
United States
Zip Code
Yusufov, Miryam; Rossi, Joseph S; Redding, Colleen A et al. (2016) Transtheoretical Model Constructs' Longitudinal Prediction of Sun Protection Over 24 Months. Int J Behav Med 23:71-83
Yusufov, Miryam; Paiva, Andrea L; Redding, Colleen A et al. (2016) Fat Reduction Efforts: A 24-Month Longitudinal Comparison of a Large Sample of Maintainers, Relapsers, and Non-Changers. Health Promot Pract 17:116-26
Redding, Colleen A; Prochaska, James O; Armstrong, Kay et al. (2015) Randomized trial outcomes of a TTM-tailored condom use and smoking intervention in urban adolescent females. Health Educ Res 30:162-78
Redding, Colleen A (2013) Towards integrated multiple behavior management for HIV and chronic conditions: a comment on Blashill et al. Ann Behav Med 46:131-2
Yin, Hui-Qing; Prochaska, James O; Rossi, Joseph S et al. (2013) Treatment-enhanced paired action contributes substantially to change across multiple health behaviors: secondary analyses of five randomized trials. Transl Behav Med 3:62-71
Greene, Geoffrey W; Redding, Colleen A; Prochaska, James O et al. (2013) Baseline transtheoretical and dietary behavioral predictors of dietary fat moderation over 12 and 24 months. Eat Behav 14:255-62
Blaney, Cerissa L; Robbins, Mark L; Paiva, Andrea L et al. (2012) Validation of the measures of the transtheoretical model for exercise in an adult African-American sample. Am J Health Promot 26:317-26
Hoeppner, Bettina B; Redding, Colleen A; Rossi, Joseph S et al. (2012) Factor structure of decisional balance and temptations scales for smoking: cross-validation in urban female African-American adolescents. Int J Behav Med 19:217-27
Redding, Colleen A; Prochaska, James O; Paiva, Andrea et al. (2011) Baseline stage, severity, and effort effects differentiate stable smokers from maintainers and relapsers. Subst Use Misuse 46:1664-74
Redding, Colleen A; Brown-Peterside, Pamela; Noar, Seth M et al. (2011) One session of TTM-tailored condom use feedback: a pilot study among at-risk women in the Bronx. AIDS Care 23:10-5

Showing the most recent 10 out of 11 publications