This proposal will test the long-term impact of the Family Check-Up (FCU) approach to preventing substance use and other high-risk problem behaviors from toddlerhood through adolescence by enhancing parenting. A critical question for a randomized prevention trial such as this is the extent to which early family support reduces adolescent alcohol and drug use (ADU), high-risk sexual behavior linked to HIV-AIDS, and serious problem behaviors in adolescence. The study also will examine how reduction in these adolescent problem behaviors is mediated by improvement in parenting and peer environments and is moderated by the family ecology and genetic risk. The proposed study will include follow-up assessments of 731 children through adolescence that include the collection of DNA;observations of family interaction;parent, youth and teacher report of adjustment;and assessments of and reports about peer environments. The Early Steps (ES) multisite sample was recruited from WIC centers in three geographically, socioeconomically, and ethnically diverse communities: Pittsburgh, PA;Charlottesville, VA;and Eugene, OR. To increase the number of sample families at risk for later ADU, eligibility was restricted to WIC families with additional socioeconomic (i.e., low parental education), family (i.e., maternal stress), and child (i.e., toddler conduct problems) risk factors. The children and families were initially assessed at child age 2 and then yearly through age 10.5, using a multi-agent and multi-method strategy that included direct observations of family interaction in most years. Families were randomly assigned to be offered a yearly FCU intervention, including adapted and tailored family management interventions. Specifically, the Family Check-Up will be evaluated as it relates to reducing adolescent substance use, high-risk sexual behavior linked to HIV, and other serious problem behavior at ages 14 and 16, how such intervention effects might be mediated by changes in parenting, and moderated by neighborhood adversity and GxE interactions.

Public Health Relevance

Substance use and related problems are critical public health issues that typically begin during adolescence. This application proposes to examine the onset of substance use, HIV-relevant risky sexual behavior, and other related problems during adolescence. The application takes advantage of an unprecedented opportunity to incorporate longitudinal data from a multi-site substance use prevention trial initiated when at-risk children were age 2 and continued through age 10.5 with 731 high-risk, low-income, ethnically-diverse children and families from urban, rural, and suburban communities. Specifically, the efficacy of the Family Check-Up will be evaluated as it relates to reducing adolescent substance use, high-risk sexual behavior linked to HIV, and other serious problem behavior at ages 14 and 16, how such intervention effects might be mediated by changes in parenting, and moderated by neighborhood adversity and GxE interactions.

Agency
National Institute of Health (NIH)
Type
Research Project (R01)
Project #
1R01DA036832-01A1
Application #
8719405
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Sims, Belinda E
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Shaw, Daniel S; Sitnick, Stephanie L; Brennan, Lauretta M et al. (2016) The long-term effectiveness of the Family Check-Up on school-age conduct problems: Moderation by neighborhood deprivation. Dev Psychopathol 28:1471-1486
Sitnick, Stephanie L; Shaw, Daniel S; Gill, Anne et al. (2015) Parenting and the Family Check-Up: Changes in Observed Parent-Child Interaction Following Early Childhood Intervention. J Clin Child Adolesc Psychol 44:970-84
Waller, Rebecca; Gardner, Frances; Shaw, Daniel S et al. (2015) Callous-unemotional behavior and early-childhood onset of behavior problems: the role of parental harshness and warmth. J Clin Child Adolesc Psychol 44:655-67
Dishion, Thomas J; Mun, Chung Jung; Drake, Emily C et al. (2015) A transactional approach to preventing early childhood neglect: The Family Check-Up as a public health strategy. Dev Psychopathol 27:1647-60
Waller, Rebecca; Gardner, Frances; Dishion, Thomas et al. (2015) Early Parental Positive Behavior Support and Childhood Adjustment: Addressing Enduring Questions with New Methods. Soc Dev 24:304-322
Smith, Justin D; Dishion, Thomas J; Shaw, Daniel S et al. (2015) Negative relational schemas predict the trajectory of coercive dynamics during early childhood. J Abnorm Child Psychol 43:693-703
Brennan, Lauretta M; Shaw, Daniel S; Dishion, Thomas J et al. (2015) The Predictive Utility of Early Childhood Disruptive Behaviors for School-Age Social Functioning. J Abnorm Child Psychol 43:1187-99
Chang, Hyein; Shaw, Daniel S; Dishion, Thomas J et al. (2014) Direct and indirect effects of the family check-up on self-regulation from toddlerhood to early school-age. J Abnorm Child Psychol 42:1117-28
Shaw, Daniel S; Shelleby, Elizabeth C (2014) Early-starting conduct problems: intersection of conduct problems and poverty. Annu Rev Clin Psychol 10:503-28
Dishion, Thomas J; Brennan, Lauretta M; Shaw, Daniel S et al. (2014) Prevention of problem behavior through annual family check-ups in early childhood: intervention effects from home to early elementary school. J Abnorm Child Psychol 42:343-54

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