Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000176-15
Application #
2124970
Study Section
Hearing Research Study Section (HAR)
Project Start
1981-07-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Physiology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Ison, James R; Allen, Paul D; Oertel, Donata (2017) Deleting the HCN1 Subunit of Hyperpolarization-Activated Ion Channels in Mice Impairs Acoustic Startle Reflexes, Gap Detection, and Spatial Localization. J Assoc Res Otolaryngol 18:427-440
Oertel, Donata; Cao, Xiao-Jie; Ison, James R et al. (2017) Cellular Computations Underlying Detection of Gaps in Sounds and Lateralizing Sound Sources. Trends Neurosci 40:613-624
Cao, Xiao-Jie; Oertel, Donata (2017) Genetic perturbations suggest a role of the resting potential in regulating the expression of the ion channels of the KCNA and HCN families in octopus cells of the ventral cochlear nucleus. Hear Res 345:57-68
Wright, Samantha; Hwang, Youngdeok; Oertel, Donata (2014) Synaptic transmission between end bulbs of Held and bushy cells in the cochlear nucleus of mice with a mutation in Otoferlin. J Neurophysiol 112:3173-88
McGinley, Matthew J; Liberman, M Charles; Bal, Ramazan et al. (2012) Generating synchrony from the asynchronous: compensation for cochlear traveling wave delays by the dendrites of individual brainstem neurons. J Neurosci 32:9301-11
Golding, Nace L; Oertel, Donata (2012) Synaptic integration in dendrites: exceptional need for speed. J Physiol 590:5563-9
Oertel, Donata; Wright, Samantha; Cao, Xiao-Jie et al. (2011) The multiple functions of T stellate/multipolar/chopper cells in the ventral cochlear nucleus. Hear Res 276:61-9
Oertel, Donata (2011) GluA4 sustains sensing of sounds through stable, speedy, sumptuous, spineless synapses. J Physiol 589:4089-90
Cao, Xiao-Jie; Oertel, Donata (2011) The magnitudes of hyperpolarization-activated and low-voltage-activated potassium currents co-vary in neurons of the ventral cochlear nucleus. J Neurophysiol 106:630-40
Cao, Xiao-Jie; Oertel, Donata (2010) Auditory nerve fibers excite targets through synapses that vary in convergence, strength, and short-term plasticity. J Neurophysiol 104:2308-20

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