Children with severe-to-profound sensorineural hearing loss (SNHL) experience significant delays across developmental domains including speech recognition, language, cognition, psychosocial interactions, and academic skills. In an attempt to avert further developmental delays, more than 4,000 American children with severe-to-profound SNHL have undergone cochlear implantation prior to the age of five and rates of implantation are accelerating. Promising clinical studies have generally supported wider application of cochlear implants in children. However, childhood implant research has often involved case-series designs, based in a single center, that evaluated children who used different implant technologies. Further, few studies have examined the impact of cochlear implants on the """"""""whole"""""""" child, particularly with longitudinal measures of cognitive, social, and behavioral development. There is also little information available on the perceived benefit of childhood implantation from a perspective of cost- effectiveness. There is a need to establish more powerful predictors of the benefits of childhood cochlear implantation. This need is underscored by the fact that clinical decisions to pursue early cochlear implantation are often prompted by parental choice. Parents of deaf children choose among options that have vastly different implications for the use of medical, (re)habilitative, educational, and other societal resources. A pressing issue concerns the validity of generalizing observed benefits in young children to populations of ever-younger deaf infants. The proposed study will systematically evaluate the predictive value of variables as they relate to outcomes of oral language acquisition, speech recognition skills, selective attention and problem-solving skills, behavioral and social development, parent-child interactions, and quality-of-life measures in children implanted in six U.S. implant centers. Data from this study will contribute to our understanding of the factors predicting implant-associated language use, communication competence in early childhood, psychosocial development, and the perceived value of early cochlear implantation in light of associated costs. Conclusions will enable a refined approach to implant candidacy when considering (re)habilitative strategies designed to optimize the development of children with severe-to-profound SNHL.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC004797-05
Application #
7046795
Study Section
Special Emphasis Panel (ZDC1-SRB-O (27))
Program Officer
Donahue, Amy
Project Start
2002-05-01
Project End
2007-07-01
Budget Start
2006-05-01
Budget End
2007-07-01
Support Year
5
Fiscal Year
2006
Total Cost
$1,611,999
Indirect Cost
Name
Johns Hopkins University
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Hoffman, Michael; Tiddens, Elena; Quittner, Alexandra L et al. (2018) Comparisons of visual attention in school-age children with cochlear implants versus hearing peers and normative data. Hear Res 359:91-100
Cejas, Ivette; Mitchell, Christine M; Hoffman, Michael et al. (2018) Comparisons of IQ in Children With and Without Cochlear Implants: Longitudinal Findings and Associations With Language. Ear Hear 39:1187-1198
Geers, Ann E; Mitchell, Christine M; Warner-Czyz, Andrea et al. (2017) Early Sign Language Exposure and Cochlear Implantation Benefits. Pediatrics 140:
Cheng, Yew Song; Kozin, Elliott D; Remenschneider, Aaron K et al. (2016) Characteristics of Wax Occlusion in the Surgical Repair of Superior Canal Dehiscence in Human Temporal Bone Specimens. Otol Neurotol 37:83-8
Hoffman, Michael F; Cejas, Ivette; Quittner, Alexandra L et al. (2016) Comparisons of Longitudinal Trajectories of Social Competence: Parent Ratings of Children With Cochlear Implants Versus Hearing Peers. Otol Neurotol 37:152-9
Quittner, Alexandra L; Cejas, Ivette; Wang, Nae-Yuh et al. (2016) Symbolic Play and Novel Noun Learning in Deaf and Hearing Children: Longitudinal Effects of Access to Sound on Early Precursors of Language. PLoS One 11:e0155964
Eisenberg, Laurie S; Fisher, Laurel M; Johnson, Karen C et al. (2016) Sentence Recognition in Quiet and Noise by Pediatric Cochlear Implant Users: Relationships to Spoken Language. Otol Neurotol 37:e75-81
Hoffman, Michael F; Quittner, Alexandra L; Cejas, Ivette (2015) Comparisons of social competence in young children with and without hearing loss: a dynamic systems framework. J Deaf Stud Deaf Educ 20:115-24
Ratjen, Felix; Bell, Scott C; Rowe, Steven M et al. (2015) Cystic fibrosis. Nat Rev Dis Primers 1:15010
Barnard, Jennifer M; Fisher, Laurel M; Johnson, Karen C et al. (2015) A Prospective Longitudinal Study of U.S. Children Unable to Achieve Open-Set Speech Recognition 5 Years After Cochlear Implantation. Otol Neurotol 36:985-92

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