Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE006533-14
Application #
2129357
Study Section
Special Emphasis Panel (ZRG4-OBM-2 (06))
Project Start
1983-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Biochemistry
Type
Schools of Dentistry
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Kirsch, T; Harrison, G; Golub, E E et al. (2000) The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage. J Biol Chem 275:35577-83
Kirsch, T; Harrison, G; Worch, K P et al. (2000) Regulatory roles of zinc in matrix vesicle-mediated mineralization of growth plate cartilage. J Bone Miner Res 15:261-70
Kirsch, T; Nah, H D; Demuth, D R et al. (1997) Annexin V-mediated calcium flux across membranes is dependent on the lipid composition: implications for cartilage mineralization. Biochemistry 36:3359-67
Golub, E E (1996) Enzymes in mineralizing systems: state of the art. Connect Tissue Res 35:183-8
Harrison, G; Shapiro, I M; Golub, E E (1995) The phosphatidylinositol-glycolipid anchor on alkaline phosphatase facilitates mineralization initiation in vitro. J Bone Miner Res 10:568-73
Yuan, Z A; Golub, E E; Collier, P M et al. (1995) Bovine enamel organ cells express tissue non-specific alkaline phosphatase mRNA. J Dent Res 74:1886-90
Chung, C H; Golub, E E; Forbes, E et al. (1992) Mechanism of action of beta-glycerophosphate on bone cell mineralization. Calcif Tissue Int 51:305-11
Matsumoto, H; Silverton, S F; Debolt, K et al. (1991) Superoxide dismutase and catalase activities in the growth cartilage: relationship between oxidoreductase activity and chondrocyte maturation. J Bone Miner Res 6:569-74
Oshima, O; Leboy, P S; McDonald, S A et al. (1989) Developmental expression of genes in chick growth cartilage detected by in situ hybridization. Calcif Tissue Int 45:182-92
Leboy, P S; Vaias, L; Uschmann, B et al. (1989) Ascorbic acid induces alkaline phosphatase, type X collagen, and calcium deposition in cultured chick chondrocytes. J Biol Chem 264:17281-6

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