The continuing controversy regarding the precise role of respiration as an influence on craniofacial growth, development and morphology affects clinical specialties such as orthodontics, maxillo-facial surgery, otorhinolaryngology, allergy and pediatrics. The major reason for this controversy is the lack of unambiguous criteria for establishing what constitutes impaired nasorespiratory function or """"""""mouth-breathing"""""""". Lacking unambiguous and objective criteria, it is difficult to confirm the presence, severity or etiology of the condition. This frequently may lead to unnecessary or inappropriate treatment. Since such treatments cannot be evaluated in terms of need or efficacy, the potential benefit of outcomes, either for orthodontic conditions or in terms of improving respiratory function, cannot be critically analyzed in terms of risk or cost. It is probable that many patients whose respiratory function falls within the range of normal physiologic variation for their age, sex and stature, receive treatments that produce no tangible benefits. Conversely, patients whose respiration may be significantly impaired, but whose craniofacial morphology appears normal or inconsistent with prevailing notions of the relationships between specific malocclusions and """"""""mouth-breathing"""""""", may fail to be identified for treatment. We have made significant progress in the quantification of respiratory mode, percent nasal breathing and nasal airway conductance. Our experimental protocols can also now yield data on the probable location of the greatest constriction within the nasal passage, which may be anywhere between the anterior nares and the nasopharynx, where the adenoids reside. We have thus established diagnostic criteria for the presence, severity and possible cause of reduced nasal airflow. The goals for these studies include (1) establishing normative standards for nasorespiratory parameters, (2) evaluating and improving diagnostic criteria for impaired function, (3) quantifying the effects of currently prevalent orthodontic and surgical treatments for impaired nasal respiration, and (4) providing new basic information to promote a better understanding of the physiology of the upper respiratory tract. With the increase in demand for orthodontic treatment, these studies have considerable clinical significance to the fields of dentistry and those medical specialties concerned with craniofacial form/function and respiration.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE006881-09
Application #
3220351
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1990-09-01
Project End
1992-11-30
Budget Start
1990-12-01
Budget End
1991-11-30
Support Year
9
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Dentistry
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Miles, P G; Vig, P S; Weyant, R J et al. (1996) Craniofacial structure and obstructive sleep apnea syndrome--a qualitative analysis and meta-analysis of the literature. Am J Orthod Dentofacial Orthop 109:163-72
Kluemper, G T; Vig, P S; Vig, K W (1995) Nasorespiratory characteristics and craniofacial morphology. Eur J Orthod 17:491-5
Vig, P S; Vig, K D (1995) Decision analysis to optimize the outcomes for Class II Division 1 orthodontic treatment. Semin Orthod 1:139-48
Vig, P S; Zajac, D J (1993) Age and gender effects on nasal respiratory function in normal subjects. Cleft Palate Craniofac J 30:279-84
Mayo, K H; Vig, K D; Vig, P S et al. (1991) Attitude variables of dentofacial deformity patients: demographic characteristics and associations. J Oral Maxillofac Surg 49:594-602
Vig, P S; Spalding, P M; Lints, R R (1991) Sensitivity and specificity of diagnostic tests for impaired nasal respiration. Am J Orthod Dentofacial Orthop 99:354-60
Han, U K; Vig, K W; Weintraub, J A et al. (1991) Consistency of orthodontic treatment decisions relative to diagnostic records. Am J Orthod Dentofacial Orthop 100:212-9
Spalding, P M; Vig, P S (1990) External nasal morphology and respiratory function. Am J Orthod Dentofacial Orthop 97:207-12
Hartgerink, D V; Vig, P S (1989) Lower anterior face height and lip incompetence do not predict nasal airway obstruction. Angle Orthod 59:17-23
Drake, A F; Keall, H; Vig, P S et al. (1988) Clinical nasal obstruction and objective respiratory mode determination. Ann Otol Rhinol Laryngol 97:397-402

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