Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK032471-12
Application #
2138828
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1982-09-01
Project End
1998-06-30
Budget Start
1996-03-31
Budget End
1996-06-30
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Smolen, J E; Hessler, R J; Nauseef, W M et al. (2001) Identification and cloning of the SNARE proteins VAMP-2 and syntaxin-4 from HL-60 cells and human neutrophils. Inflammation 25:255-65
Smolen, J E; Petersen, T K; Koch, C et al. (2000) L-selectin signaling of neutrophil adhesion and degranulation involves p38 mitogen-activated protein kinase. J Biol Chem 275:15876-84
Hessler, R J; Blackwood, R A; Brock, T G et al. (1998) Identification of glyceraldehyde-3-phosphate dehydrogenase as a Ca2+-dependent fusogen in human neutrophil cytosol. J Leukoc Biol 63:331-6
Blackwood, R A; Transue, A T; Harsh, D M et al. (1996) PLA2 promotes fusion between PMN-specific granules and complex liposomes. J Leukoc Biol 59:663-70
Blackwood, R A; Smolen, J E; Hessler, R J et al. (1996) Development of an aqueous-space mixing assay for fusion of granules and plasma membranes from human neutrophils. Biochem J 314 ( Pt 2):469-75
Francis, J W; Balazovich, K J; Smolen, J E et al. (1992) Human neutrophil annexin I promotes granule aggregation and modulates Ca(2+)-dependent membrane fusion. J Clin Invest 90:537-44
Smolen, J E; Stoehr, S J; Kuczynski, B (1991) Cyclic AMP inhibits secretion from electroporated human neutrophils. J Leukoc Biol 49:172-9
Smolen, J E; Stoehr, S J; Kuczynski, B et al. (1991) Dual effects of guanosine 5'-[gamma-thio]triphosphate on secretion by electroporated human neutrophils. Biochem J 279 ( Pt 3):657-64
Stoehr, S J; Smolen, J E; Suchard, S J (1990) Lipocortins are major substrates for protein kinase C in extracts of human neutrophils. J Immunol 144:3936-45
Stoehr, S J; Smolen, J E (1990) Human neutrophils contain a protein kinase C-like enzyme that utilizes guanosine triphosphate as a phosphate donor. Cofactor requirements, kinetics, and endogenous acceptor proteins. Blood 75:479-87

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