Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK042284-04A1
Application #
2142214
Study Section
Special Emphasis Panel (ZRG2-BPO (01))
Project Start
1993-01-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Faulconbridge, Lucy F; Grill, Harvey J; Kaplan, Joel M et al. (2008) Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus. Brain Res 1218:151-7
Williams, D L; Grill, H J; Cummings, D E et al. (2006) Overfeeding-induced weight gain suppresses plasma ghrelin levels in rats. J Endocrinol Invest 29:863-8
Faulconbridge, Lucy F; Grill, Harvey J; Kaplan, Joel M (2005) Distinct forebrain and caudal brainstem contributions to the neuropeptide Y mediation of ghrelin hyperphagia. Diabetes 54:1985-93
Grill, Harvey J; Carmody, Jill S; Amanda Sadacca, L et al. (2004) Attenuation of lipopolysaccharide anorexia by antagonism of caudal brain stem but not forebrain GLP-1-R. Am J Physiol Regul Integr Comp Physiol 287:R1190-3
Daniels, Derek; Markison, Stacy; Grill, Harvey J et al. (2004) Central structures necessary and sufficient for ingestive and glycemic responses to Urocortin I administration. J Neurosci 24:11457-62
Williams, Diana L; Cummings, David E; Grill, Harvey J et al. (2003) Meal-related ghrelin suppression requires postgastric feedback. Endocrinology 144:2765-7
Faulconbridge, Lucy F; Cummings, David E; Kaplan, Joel M et al. (2003) Hyperphagic effects of brainstem ghrelin administration. Diabetes 52:2260-5
Williams, Diana L; Grill, Harvey J; Cummings, David E et al. (2003) Vagotomy dissociates short- and long-term controls of circulating ghrelin. Endocrinology 144:5184-7
Williams, D L; Bowers, R R; Bartness, T J et al. (2003) Brainstem melanocortin 3/4 receptor stimulation increases uncoupling protein gene expression in brown fat. Endocrinology 144:4692-7
Grill, Harvey J; Schwartz, Michael W; Kaplan, Joel M et al. (2002) Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. Endocrinology 143:239-46

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