Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK046285-03
Application #
2145471
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1994-05-15
Project End
1998-04-30
Budget Start
1996-06-05
Budget End
1998-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Surgery
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Cattaruzza, Fiore; Johnson, Cali; Leggit, Alan et al. (2013) Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol 304:G1002-12
Lyo, Victoria; Cattaruzza, Fiore; Kim, Tyson N et al. (2012) Active cathepsins B, L, and S in murine and human pancreatitis. Am J Physiol Gastrointest Liver Physiol 303:G894-903
Cattaruzza, Fiore; Lyo, Victoria; Jones, Ella et al. (2011) Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice. Gastroenterology 141:1864-74.e1-3
Ceppa, Eugene P; Lyo, Victoria; Grady, Eileen F et al. (2011) Serine proteases mediate inflammatory pain in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol 300:G1033-42
Eilers, Helge; Cattaruzza, Fiore; Nassini, Romina et al. (2010) Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesia and neurogenic bronchoconstriction. Anesthesiology 112:1452-63
Vergnolle, N; Cenac, N; Altier, C et al. (2010) A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation. Br J Pharmacol 159:1161-73
Ceppa, Eugene; Cattaruzza, Fiore; Lyo, Victoria et al. (2010) Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol 299:G556-71
Wick, Elizabeth C; Pikios, Stella; Grady, Eileen F et al. (2006) Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis. Surgery 139:197-201
Wick, Elizabeth C; Hoge, Steven G; Grahn, Sarah W et al. (2006) Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol 290:G959-69
Hutter, Matthew M; Wick, Elizabeth C; Day, Amy Lightner et al. (2005) Transient receptor potential vanilloid (TRPV-1) promotes neurogenic inflammation in the pancreas via activation of the neurokinin-1 receptor (NK-1R). Pancreas 30:260-5

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