The objective of this proposal is to develop a practical flat-panel x-ray imaging detector with programmable gain in order to address the increasing demand for wide dynamic range flat panel detectors in advanced x-ray imaging applications. The proposed detector employs three major components: a structured cesium iodide (CsI) scintillator to convert x-rays to optical photons;an avalanche amorphous selenium (a-Se) photoconductor, HARP (High-gain Avalanche Rushing amorphous Photoconductor), to convert the optical image to charge and provide a programmable gain;and a large area active matrix (AM) thin film transistor (TFT) array to read out the image electronically in real-time. The proposed detector has been named SHARP-AMFPI (Scintillator-HARP Active Matrix Flat-Panel Imager). It is capable of producing x-ray quantum noise limited images at the lowest dose expected for x-ray imaging (0.1

Public Health Relevance

In the proposed work we will develop the next generation x-ray flat-panel detectors for low dose imaging. It will increase the efficiency of x-ray detection in fluoroscopy by up to 5 times while maintaining the capability for dual mode fluoroscopy/radiography operation by virtue of programmable gain.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Research Project (R01)
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Special Emphasis Panel (ZRG1-SBIB-P (02))
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Lopez, Hector
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State University New York Stony Brook
Schools of Medicine
Stony Brook
United States
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Hu, Yue-Houng; Zhao, Wei (2014) The effect of amorphous selenium detector thickness on dual-energy digital breast imaging. Med Phys 41:111904
Goldan, A H; Zhao, W (2013) A field-shaping multi-well avalanche detector for direct conversion amorphous selenium. Med Phys 40:010702
Xiang, Liangzhong; Han, Bin; Carpenter, Colin et al. (2013) X-ray acoustic computed tomography with pulsed x-ray beam from a medical linear accelerator. Med Phys 40:010701
Hu, Yue-Houng; Zhao, Wei (2011) The effect of angular dose distribution on the detection of microcalcifications in digital breast tomosynthesis. Med Phys 38:2455-66
Wronski, M M; Zhao, W; Reznik, A et al. (2010) A solid-state amorphous selenium avalanche technology for low photon flux imaging applications. Med Phys 37:4982-5
Lia, Dan; Zhao, Wei; Nanba, Masakazu et al. (2009) Scintillator avalanche photoconductor with high resolution emitter readout for low dose x-ray imaging: lag. Med Phys 36:4047-58
Zhao, Bo; Zhou, Jun; Hu, Yue-Houng et al. (2009) Experimental validation of a three-dimensional linear system model for breast tomosynthesis. Med Phys 36:240-51
Hu, Yue-Houng; Zhao, Bo; Zhao, Wei (2008) Image artifacts in digital breast tomosynthesis: investigation of the effects of system geometry and reconstruction parameters using a linear system approach. Med Phys 35:5242-52
Wronski, M M; Rowlands, J A (2008) Direct-conversion flat-panel imager with avalanche gain: feasibility investigation for HARP-AMFPI. Med Phys 35:5207-18
Zhao, Bo; Zhao, Wei (2008) Three-dimensional linear system analysis for breast tomosynthesis. Med Phys 35:5219-32

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